Fig. 5

EPCs promoted LPS-induced MPMVEC proliferation via miR-10a/b-5p/ADAM15. The MPMVECs were co-transfected with miR-10a-5p inhibitor, miR-10b-5p inhibitor and si-ADAM15 followed by EPCs co-culture and LPS stimulation. a: The protein level of ADAM15 was determined by western blot analysis. b: Cell proliferation was determined by MTT assay. *p < 0.05 vs. control; #p < 0.05 vs. LPS; & p < 0.05 vs. LPS + EPC + NC; $ p < 0.05 vs. LPS + EPC + miR-a-5p inhibitor+miR-10b-5p inhibitor+si-control