Fig. 6

EPCs exerted the therapeutic effect of ALI via regulating miR-10a/b-5p/ADAM15. The IT administration of miR-10a-5p and miR-10b-5p inhibitors (2 mg/kg) was performed 24 h before the IT instillation of LPS and IV injection of EPCs. a: The level of lung wet-to-dry ratio and the average value of LIS. b: The expression of miR-10a/b-5p and ADAM15 was determined by qRT-PCR and western blot analysis. *p < 0.05 vs. sham; #p < 0.05 vs. ALI; & p < 0.05 vs. ALI + EPC + NC