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Table 1 Characteristics of the obese patients and normal weight controls. The data are presented as the mean (± standard deviations) and median (min-max) values

From: Association of intracellular lipid accumulation in subcutaneous adipocyte precursors and plasma adipokines in bariatric surgery candidates

Parameter Normal weight controls (N = 7) Obese patients (N = 20) P- value
Age (years) 42.0 (10.7)/42.0 (25–58)) 42.1 (9.9)/45.5 (23–63) 0.978
BMI (kg/m2) 24.5 (2.5)/24.7 (21.2–29.0) 45.0 (6.3)/43.7 (36.4–58.9) < 0.001
Lipid profile:
 Total cholesterol (TC)(mg/dl) 166.7 (18.3)/159.0 (151–202) 210.6 (32.1)/212.5 (138–265) 0.006
 LDL-cholesterol (LDL)(mg/dl) 90.0 (2.8)/90.0 (86–93) 141.0 (29.0)/139.5 (80–184) 0.001
 HDL-cholesterol (HDL)(mg/dl) 54.2 (3.7)/54.0 (48–59) 49.7 (12.2)/49.0 (23–75) 0.223
 TC/HDL (Normal< 4) 3.1 (0.3)/3.1 (2.7–3.4) 4.4 (1.0)/(3.1–6.2) 0.001
 Triglycerides (TG) (mg/dl) 96.3 (14.4)/93.0 (73–115) 165.3 (103.5)/140.5 (69–448) 0.025
Glucose homeostasis:
 Fasting plasma glucose (mg/dl) 86.9 (8.9)/87.0 (73–99) 126.8 (74.1)/102.0 (77–362) 0.012
 Insulin (μIU/ml) 7.4 (1.6)/6.89 (6.3–10.7) 16.8 (9.1)/15.8 (6.0–43.4) 0.003
 C-peptide (ng/ml) 1.6 (0.3)/1.5 (1.2–2.1) 3.2 (1.0)/3.5 (1.2–4.9) 0.013
 HOMA-IR 1.6 (0.4)/1.5 (1.3–2.5) 6.1 (7.0)/3.8 (1.4–28.7) 0.001
Plasma hormones
 Morning Cortisol (μg/dl) 10.1 (3.7)/9.6 (6.2–15.6) 12.9 (4.1)/12.4 (7.6–23.4) 0.072
 Leptin (ng/dl) 5.7 (2.0)/6.0 (2.8–8.0) 26.5 (8.8)/27.6 (8.0–39.6) < 0.001
 Adiponectin (μg/dl) 30.6 (2.0)/30.9 (2.7–3.4) 29.0 (3.2)/29.1 (1.9–3.3) 0.166
 Leptin: Adiponectin Ratio 0.18 (0.7)/1.9 (0.9–2.7) 0.93 (0.3)/1.0 (2.6–14.4) < 0.001
Adipocyte differentiation dysfunction
 Lipid accumulation (OD492) 0.71 (0.1)/0.75 (0.50–0.82) 0.49 (0.6)/0.48 (0.41–0.67) < 0.001
  1. P-values were assessed by Mann–Whitney test to compare non-normal distributed variables
  2. P-value ≤ 0.05 was considered significant