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Table 1 Characteristics of the obese patients and normal weight controls. The data are presented as the mean (± standard deviations) and median (min-max) values

From: Association of intracellular lipid accumulation in subcutaneous adipocyte precursors and plasma adipokines in bariatric surgery candidates

Parameter

Normal weight controls (N = 7)

Obese patients (N = 20)

P- value

Age (years)

42.0 (10.7)/42.0 (25–58))

42.1 (9.9)/45.5 (23–63)

0.978

BMI (kg/m2)

24.5 (2.5)/24.7 (21.2–29.0)

45.0 (6.3)/43.7 (36.4–58.9)

< 0.001

Lipid profile:

 Total cholesterol (TC)(mg/dl)

166.7 (18.3)/159.0 (151–202)

210.6 (32.1)/212.5 (138–265)

0.006

 LDL-cholesterol (LDL)(mg/dl)

90.0 (2.8)/90.0 (86–93)

141.0 (29.0)/139.5 (80–184)

0.001

 HDL-cholesterol (HDL)(mg/dl)

54.2 (3.7)/54.0 (48–59)

49.7 (12.2)/49.0 (23–75)

0.223

 TC/HDL (Normal< 4)

3.1 (0.3)/3.1 (2.7–3.4)

4.4 (1.0)/(3.1–6.2)

0.001

 Triglycerides (TG) (mg/dl)

96.3 (14.4)/93.0 (73–115)

165.3 (103.5)/140.5 (69–448)

0.025

Glucose homeostasis:

 Fasting plasma glucose (mg/dl)

86.9 (8.9)/87.0 (73–99)

126.8 (74.1)/102.0 (77–362)

0.012

 Insulin (μIU/ml)

7.4 (1.6)/6.89 (6.3–10.7)

16.8 (9.1)/15.8 (6.0–43.4)

0.003

 C-peptide (ng/ml)

1.6 (0.3)/1.5 (1.2–2.1)

3.2 (1.0)/3.5 (1.2–4.9)

0.013

 HOMA-IR

1.6 (0.4)/1.5 (1.3–2.5)

6.1 (7.0)/3.8 (1.4–28.7)

0.001

Plasma hormones

 Morning Cortisol (μg/dl)

10.1 (3.7)/9.6 (6.2–15.6)

12.9 (4.1)/12.4 (7.6–23.4)

0.072

 Leptin (ng/dl)

5.7 (2.0)/6.0 (2.8–8.0)

26.5 (8.8)/27.6 (8.0–39.6)

< 0.001

 Adiponectin (μg/dl)

30.6 (2.0)/30.9 (2.7–3.4)

29.0 (3.2)/29.1 (1.9–3.3)

0.166

 Leptin: Adiponectin Ratio

0.18 (0.7)/1.9 (0.9–2.7)

0.93 (0.3)/1.0 (2.6–14.4)

< 0.001

Adipocyte differentiation dysfunction

 Lipid accumulation (OD492)

0.71 (0.1)/0.75 (0.50–0.82)

0.49 (0.6)/0.48 (0.41–0.67)

< 0.001

  1. P-values were assessed by Mann–Whitney test to compare non-normal distributed variables
  2. P-value ≤ 0.05 was considered significant