Variable | Case | control | t | p |
---|---|---|---|---|
CC genotype | n = 213 | n = 253 |  |  |
 Folic acid, nmol/L | 36.49 ± 6.47 | 35.29 ± 21.53 | 0.78 | 0.434 |
 Vitamin B12, pg/ml | 347.23 ± 114.82 | 346.84 ± 124.51 | 0.03 | 0.976 |
 Homocysteine, umol/L | 10.33 ± 4.34 | 10.83 ± 3.38 | −1.39 | 0.165 |
 Total protein, g/L | 72.87 ± 4.78 | 70.69 ± 9.99 | 2.93 | 0.004 |
 Total cholesterol, mmol/L | 4.48 ± 1.09 | 4.51 ± 2.13 | −0.16 | 0.873 |
 Triglyceride, mmol/L | 1.06 ± 0.81 | 1.03 ± 0.57 | 0.68 | 0.494 |
 High-density lipoprotein cholesterol, mmol/L | 1.68 ± 0.42 | 1.74 ± 0.36 | −1.81 | 0.071 |
 Low-density lipoprotein cholesterol, mmol/L | 2.65 ± 0.84 | 2.16 ± 0.60 | 1.78 | 0.082 |
 Fasting glucose, mmol/L | 4.93 ± 0.38 | 4.92 ± 0.29 | 0.26 | 0.798 |
 Fasting insulin, pmol/L | 70.64 ± 14.43 | 67.90 ± 14.03 | 2.08 | 0.038 |
 HOMR-IR | 2.21 ± 0.45 | 2.12 ± 0.42 | 2.12 | 0.035 |
 IL6, pg/ml | 81.84 ± 339.77 | 33.09 ± 215.37 | 1.89 | 0.058 |
 TNFα, pg/ml | 29.11 ± 88.72 | 18.86 ± 30.27 | 1.75 | 0.081 |
CT genotype | n = 153 | n = 78 |  |  |
 Folic acid, nmol/L | 32.73 ± 7.85 | 38.43 ± 9.29 | −3.55 | 0.000 |
 Vitamin B12, pg/ml | 359.98 ± 131.88 | 353.94 ± 115.88 | 0.33 | 0.745 |
 Homocysteine, umol/L | 12.65 ± 3.97 | 11.71 ± 3.06 | 1.99 | 0.047 |
 Total protein, g/L | 71.68 ± 8.05 | 70.61 ± 8.01 | 0.92 | 0.361 |
 Total cholesterol, mmol/L | 6.99 ± 32.56 | 4.17 ± 0.81 | 0.72 | 0.475 |
 Triglyceride, mmol/L | 1.02 ± 0.52 | 0.95 ± 0.37 | 0.97 | 0.332 |
 High-density lipoprotein cholesterol, mmol/L | 1.67 ± 0.33 | 1.72 ± 0.48 | −0.92 | 0.358 |
 Low-density lipoprotein cholesterol, mmol/L | 2.59 ± 0.78 | 2.39 ± 0.74 | 1.82 | 0.070 |
 Fasting glucose, mmol/L | 4.95 ± 0.37 | 4.88 ± 0.39 | 0.62 | 0.532 |
 Fasting insulin, pmol/L | 72.28 ± 15.42 | 66.89 ± 12.57 | 2.86 | 0.005 |
 HOMR-IR | 2.27 ± 0.47 | 2.11 ± 0.36 | 2.83 | 0.005 |
 IL6, pg/ml | 72.60 ± 275.52 | 41.08 ± 147.43 | 1.09 | 0.276 |
 TNFα, pg/ml | 29.34 ± 106.30 | 16.52 ± 34.81 | 1.25 | 0.210 |
TT genotype | n = 37 | n = 11 |  |  |
 Folic acid, nmol/L | 25.72 ± 7.67 | 24.54 ± 7.84 | 0.45 | 0.658 |
 Vitamin B12, pg/ml | 354.14 ± 142.24 | 322.82 ± 167.57 | 0.62 | 0.541 |
 Homocysteine, umol/L | 17.80 ± 2.86 | 15.93 ± 2.08 | 2.39 | 0.026 |
 Total protein, g/L | 70.17 ± 9.96 | 70.42 ± 3.79 | −0.08 | 0.933 |
 Total cholesterol, mmol/L | 4.34 ± 1.01 | 3.96 ± 0.80 | 1.13 | 0.265 |
 Triglyceride, mmol/L | 1.11 ± 0.57 | 1.49 ± 0.73 | −1.85 | 0.071 |
 High-density lipoprotein cholesterol, mmol/L | 1.58 ± 0.33 | 1.62 ± 0.26 | −0.31 | 0.761 |
 Low-density lipoprotein cholesterol, mmol/L | 2.61 ± 0.76 | 2.43 ± 0.67 | 2.78 | 0.006 |
 Fasting glucose, mmol/L | 4.95 ± 0.43 | 4.79 ± 0.36 | 1.38 | 0.175 |
 Fasting insulin, pmol/L | 70.52 ± 16.13 | 67.86 ± 17.26 | 0.55 | 0.583 |
 HOMR-IR | 2.21 ± 0.45 | 2.07 ± 0.54 | 0.96 | 0.341 |
 IL6, pg/ml | 14.94 ± 43.01 | 104.44 ± 273.61 | −1.58 | 0.126 |
 TNFα, pg/ml | 15.72 ± 29.57 | 20.42 ± 19.78 | −0.65 | 0.521 |
CT /TTgenotype | n = 190 | n = 89 |  |  |
 Folic acid, nmol/L | 31.31 ± 8.99 | 35.11 ± 21.36 | −2.96 | 0.003 |
 Vitamin B12, pg/ml | 358.84 ± 133.59 | 349.61 ± 123.50 | 0.53 | 0.598 |
 Homocysteine, umol/L | 12.37 ± 4.57 | 11.52 ± 3.65 | 2.52 | 0.012 |
 Total protein, g/L | 71.39 ± 8.45 | 70.59 ± 7.55 | 0.73 | 0.465 |
 Total cholesterol, mmol/L | 6.48 ± 29.22 | 4.14 ± 0.81 | 0.71 | 0.478 |
 Triglyceride, mmol/L | 1.04 ± 0.53 | 1.03 ± 0.47 | 0.14 | 0.887 |
 High-density lipoprotein cholesterol, mmol/L | 1.66 ± 0.34 | 1.71 ± 0.45 | −1.08 | 0.281 |
 Low-density lipoprotein cholesterol, mmol/L | 2.61 ± 0.79 | 2.36 ± 0.72 | 2.38 | 0.018 |
 Fasting glucose, mmol/L | 4.95 ± 0.38 | 4.94 ± 0.39 | 0.15 | 0.158 |
 Fasting insulin, pmol/L | 71.99 ± 15.50 | 67.08 ± 13.55 | 2.78 | 0.006 |
 HOMR-IR | 2.26 ± 0.47 | 2.11 ± 0.40 | 2.96 | 0.003 |
 IL6, pg/ml | 63.25 ± 253.50 | 53.54 ± 119.70 | 0.37 | 0.714 |
 TNFα, pg/ml | 15.72 ± 29.57 | 20.42 ± 19.78 | −0.65 | 0.521 |