Variable | Case | control | t | p |
---|---|---|---|---|
AA genotype | n = 231 | n = 221 |  | |
 Folic acid, nmol/L | 31.28 ± 9.77 | 33.89 ± 23.08 | −1.58 | 0.115 |
 Vitamin B12, pg/ml | 352.21 ± 125.06 | 347.58 ± 124.71 | 0.39 | 0.694 |
 Homocysteine, umol/L | 11.93 ± 4.63 | 11.27 ± 2.75 | 1.81 | 0.071 |
 Total protein, g/L | 71.91 ± 7.99 | 70.26 ± 10.93 | 1.83 | 0.067 |
 Total cholesterol, mmol/L | 4.32 ± 0.84 | 4.47 ± 2.08 | −1.05 | 0.295 |
 Triglyceride, mmol/L | 1.07 ± 0.77 | 1.06 ± 0.59 | 0.13 | 0.894 |
 High-density lipoprotein cholesterol, mmol/L | 1.67 ± 0.39 | 1.76 ± 0.40 | −2.51 | 0.012 |
 Low-density lipoprotein cholesterol, mmol/L | 2.56 ± 0.74 | 2.45 ± 0.71 | 1.65 | 0.101 |
 Fasting glucose, mmol/L | 4.92 ± 0.37 | 4.92 ± 0.38 | 0.02 | 0.987 |
 Fasting insulin, pmol/L | 72.88 ± 14.93 | 67.83 ± 14.42 | 3.55 | < 0.001 |
 HOMR-IR | 2.28 ± 0.46 | 2.12 ± 0.43 | 3.74 | < 0.001 |
 IL6, pg/ml | 58.24 ± 239.93 | 36.23 ± 138.03 | 1.19 | 0.235 |
 TNFα, pg/ml | 29.47 ± 108.57 | 19.73 ± 35.54 | 1.29 | 0.198 |
AC genotype | n = 144 | n = 102 |  |  |
 Folic acid, nmol/L | 34.18 ± 6.80 | 35.24 ± 6.50 | −1.23 | 0.218 |
 Vitamin B12, pg/ml | 354.39 ± 129.77 | 350.37 ± 116.89 | 0.25 | 0.804 |
 Homocysteine, umol/L | 11.85 ± 4.63 | 11.06 ± 4.35 | 1.49 | 0.137 |
 Total protein, g/L | 72.69 ± 4.52 | 71.63 ± 6.12 | 1.52 | 0.129 |
 Total cholesterol, mmol/L | 7.41 ± 33.55 | 4.21 ± 1.23 | 0.96 | 0.337 |
 Triglyceride, mmol/L | 1.07 ± 0.59 | 0.96 ± 0.44 | 1.54 | 0.126 |
 High-density lipoprotein cholesterol, mmol/L | 1.65 ± 0.36 | 1.70 ± 0.35 | −1.15 | 0.252 |
 Low-density lipoprotein cholesterol, mmol/L | 2.73 ± 0.83 | 2.34 ± 0.65 | 3.88 | 0.000 |
 Fasting glucose, mmol/L | 4.95 ± 0.39 | 4.94 ± 0.42 | 0.16 | 0.873 |
 Fasting insulin, pmol/L | 68.94 ± 14.64 | 67.46 ± 13.49 | 0.03 | 0.409 |
 HOMR-IR | 2.16 ± 0.43 | 2.11 ± 0.40 | 0.89 | 0.372 |
 IL6, pg/ml | 109.82 ± 422.09 | 51.87 ± 305.40 | 1.26 | 0.208 |
 TNFα, pg/ml | 28.91 ± 69.92 | 15.59 ± 21.63 | 2.16 | 0.032 |
CC genotype | n = 28 | n = 19 |  |  |
 Folic acid, nmol/L | 33.18 ± 9.09 | 34.99 ± 8.43 | −0.69 | 0.494 |
 Vitamin B12, pg/ml | 348.11 ± 80.49 | 330.79 ± 157.10 | 0.50 | 0.622 |
 Homocysteine, umol/L | 12.43 ± 5.99 | 11.84 ± 4.58 | 0.36 | 0.717 |
 Total protein, g/L | 71.67 ± 4.22 | 70.19 ± 4.62 | 1.14 | 0.262 |
 Total cholesterol, mmol/L | 4.27 ± 0.74 | 4.93 ± 2.66 | −1.23 | 0.226 |
 Triglyceride, mmol/L | 0.89 ± 0.37 | 1.00 ± 0.49 | −0.91 | 0.366 |
 High-density lipoprotein cholesterol, mmol/L | 1.78 ± 0.42 | 1.62 ± 0.32 | 1.44 | 0.156 |
 Low-density lipoprotein cholesterol, mmol/L | 2.41 ± 0.67 | 2.38 ± 0.53 | 0.16 | 0.876 |
 Fasting glucose, mmol/L | 4.93 ± 0.38 | 5.00 ± 0.35 | −0.81 | 0.420 |
 Fasting insulin, pmol/L | 68.09 ± 13.33 | 66.68 ± 11.63 | 0.45 | 0.657 |
 HOMR-IR | 2.14 ± 0.46 | 2.12 ± 0.36 | 0.24 | 0.809 |
 IL6, pg/ml | 37.96 ± 81.36 | 30.61 ± 91.73 | 0.34 | 0.735 |
 TNFα, pg/ml | 17.62 ± 22.33 | 18.33 ± 27.97 | −0.11 | 0.910 |
AC /CCgenotype | n = 172 | n = 121 |  |  |
 Folic acid, nmol/L | 34.02 ± 7.20 | 35.20 ± 6.80 | −1.42 | 0.155 |
 Vitamin B12, pg/ml | 353.37 ± 122.93 | 347.30 ± 23.50 | 0.42 | 0.678 |
 Homocysteine, umol/L | 11.86 ± 4.63 | 11.06 ± 4.35 | 1.49 | 0.137 |
 Total protein, g/L | 72.52 ± 4.73 | 71.40 ± 5.92 | 1.80 | 0.073 |
 Total cholesterol, mmol/L | 6.92 ± 30.79 | 4.32 ± 1.55 | 0.93 | 0.356 |
 Triglyceride, mmol/L | 1.04 ± 0.57 | 0.96 ± 0.45 | 1.14 | 0.253 |
 High-density lipoprotein cholesterol, mmol/L | 1.67 ± 0.37 | 1.68 ± 0.35 | −0.42 | 0.672 |
 Low-density lipoprotein cholesterol, mmol/L | 2.67 ± 0.81 | 2.35 ± 0.63 | 3.69 | 0.000 |
 Fasting glucose, mmol/L | 4.94 ± 0.39 | 4.95 ± 0.40 | −0.22 | 0.826 |
 Fasting insulin, pmol/L | 68.79 ± 14.39 | 67.27 ± 13.02 | 0.98 | 0.325 |
 HOMR-IR | 2.16 ± 0.43 | 2.11 ± 0.39 | 0.93 | 0.351 |
 IL6, pg/ml | 97.57 ± 386.58 | 46.67 ± 269.04 | 1.37 | 0.170 |
 TNFα, pg/ml | 26.98 ± 64.43 | 16.26 ± 23.26 | 2.04 | 0.042 |