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Table 1 Anthropometrical characteristics and laboratory tests from participating individuals

From: Association of Omentin rs2274907 and FTO rs9939609 gene polymorphisms with insulin resistance in Iranian individuals with newly diagnosed type 2 diabetes

Parameters a

Case (n = 83)

Control (n = 85)

P value

Age (years)

50.95 ± 11.84

50.51 ± 11.7

0.806

Gender (female %)

63.8%

64.7%

0.909

Familial history of diabetes (%)

77.1%

32.9%

0.0001

Hypertension (%)

51.8%

17.6%

0.0001

Smoking (%)

26.5%

14.1%

0.055

BMI

28.26 ± 2.81

24.55 ± 1.39

0.001

FBG (mmol/L) b

9.45 ± 2.56

4.99 ± 0.54

0.0001

Insulin (μIU/ml) b

13.45 ± 5.97

10.05 ± 4.9

0.094

HOMA-IRb

5.39 ± 1.37

2.3 ± 1.89

0.0001

TG (mg/dl) c

221.6 ± 47.7

134.2 ± 28.9

0.0001

Total cholesterol (mg/dl) c

184.4 ± 38.2

158.5 ± 32.0

0.125

LDL (mg/dl) c

97.4 ± 31.2

86.4 ± 24.9

0.083

HDL (mg/dl) c

39.4 ± 10.8

40.4 ± 8.9

0.545

TC/HDL ratio c

4.85 ± 1.4

4.03 ± 0.92

0.096

LDL/HDL ratio c

2.55 ± 0.82

2.20 ± 0.71

0.085

FTO rs9939609 polymorphism (% polymorphic allele)

39.2%

20%

0.0001

Omentin rs2274907 polymorphism (% polymorphic allele)

27.1%

15.8%

0.011

  1. a Data are expressed as arithmetic mean ± SD
  2. b Diabetes screening tests reference values: Fasting Blood Glucose (FBG) Normal: 3.9–5.5, Prediabetic: 5.6–6.9, Diabetes ≥7; Insulin: 2–25; Homeostatic Model Assessment of Insulin Resistance (HOMA-IR): Normal: < 2.0, Moderate IR: 2.0–4.5, Severe IR: > 4.5;
  3. c Lipid panel reference values: Triglyceride (TG): Normal: < 150, Borderline: 150–199, High: 200–499, Very high: > 500; Total cholesterol (TC): Normal: < 200, Borderline: 200–239, High: > 240; Low density lipoprotein (LDL): Optimal: < 100, Near optimal: 100–129, Borderline: 130–159, High: 160–189, Very high: > 190; High density lipoprotein (HDL): Low: < 40, Normal: 40–60, High: > 60; Total cholesterol/High density lipoprotein ratio (TC/HDL): Low risk < 5, Average risk < 5–7, High risk > 7, Very high risk > 11; Low density lipoprotein/ High density lipoprotein ratio (LDL/HDL): Low risk: < 3.4, Average risk: 3.4–5, High risk > 5