Parameters a | Case (n = 83) | Control (n = 85) | P value |
---|---|---|---|
Age (years) | 50.95 ± 11.84 | 50.51 ± 11.7 | 0.806 |
Gender (female %) | 63.8% | 64.7% | 0.909 |
Familial history of diabetes (%) | 77.1% | 32.9% | 0.0001 |
Hypertension (%) | 51.8% | 17.6% | 0.0001 |
Smoking (%) | 26.5% | 14.1% | 0.055 |
BMI | 28.26 ± 2.81 | 24.55 ± 1.39 | 0.001 |
FBG (mmol/L) b | 9.45 ± 2.56 | 4.99 ± 0.54 | 0.0001 |
Insulin (μIU/ml) b | 13.45 ± 5.97 | 10.05 ± 4.9 | 0.094 |
HOMA-IRb | 5.39 ± 1.37 | 2.3 ± 1.89 | 0.0001 |
TG (mg/dl) c | 221.6 ± 47.7 | 134.2 ± 28.9 | 0.0001 |
Total cholesterol (mg/dl) c | 184.4 ± 38.2 | 158.5 ± 32.0 | 0.125 |
LDL (mg/dl) c | 97.4 ± 31.2 | 86.4 ± 24.9 | 0.083 |
HDL (mg/dl) c | 39.4 ± 10.8 | 40.4 ± 8.9 | 0.545 |
TC/HDL ratio c | 4.85 ± 1.4 | 4.03 ± 0.92 | 0.096 |
LDL/HDL ratio c | 2.55 ± 0.82 | 2.20 ± 0.71 | 0.085 |
FTO rs9939609 polymorphism (% polymorphic allele) | 39.2% | 20% | 0.0001 |
Omentin rs2274907 polymorphism (% polymorphic allele) | 27.1% | 15.8% | 0.011 |