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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1

Fig. 4

Hematoxylin & Eosin-stained images of spleen tissue of a sham-treated and treated Npc1+/+ (a, e and high magnification a, f) and of a sham-treated and treated Npc1−/− mouse (c, g and high magnification d, h). Note the foam cells in the spleen tissue of a sham-treated Npc1−/− mouse (c, d), and the amelioration in the spleen tissue of treated Npc1−/− mouse (g, h). A scale bar is shown in g, which also applies to a,c,e: 100 μm and in h, also applies to b,d,f: 50 μm

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