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Fig. 9 | Lipids in Health and Disease

Fig. 9

From: A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1

Fig. 9

Paraffin sections from spleen of sham-treated and treated Npc1+/+ and Npc1−/− mouse were immuniohistochemically analyzed with B cell marker CD45R (a, c, e, g) and T cell marker CD3 (b, d, f, h). The brown areas are positive reactions stained by DAB, counter stained with hematoxylin. Sham-treated Npc1−/− demonstrated a different allocation of B cells (c) and T cells (d). This allocation was reversible after treatment. Scale bar: H: 50 μm and also applies to a-g

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