Skip to main content

Advertisement

Table 2 The differences of clinical parameters across three groups dividing by serum FFAs

From: Evaluation of serum free fatty acids in chronic renal failure: evidence from a rare case with undetectable serum free fatty acids and population data

Parameter FFA-reduced group (n = 78) FFA-normal group (n = 450) FFA-increased group (n = 46) P-value
Age (year) 59.3± 1.9 66.0(52.0–76.0) 66.4 ± 2.2 0.053
Liver function
 ALT (U/L) 16.50(10.00–25.25) 13.00(8.00–20.00) 12.00(7.75–19.25) 0.091
 AST (U/L) 18.00(12.75–25.25) 18.00(14.00–25.00) 22.00(15.5–33.25) 0.078
 AST/ALT 1.17(0.81–1.68) 1.38(1.00–1.75) 1.87(1.00–2.86) 0.001
 TBIL (μmol/L) 8.15(6.70–10.48) 8.50(7.10–11.30) 10.45(8.50–15.65) < 0.001
 DBIL (μmol/L) 1.35(1.00–2.10) 1.50(1.10–2.20) 2.25(1.58–4.15) < 0.001
 UBIL (μmol/L) 6.80(5.70–8.53) 7.00(5.83–8.90) 8.05(6.93–12.15) 0.004
 TP (g/L) 62.25(59.70–68.60) 64.50(58.90–70.10) 65.58 ± 1.12 0.169
 Albumin (g/L) 33.94 ± 0.63 34.80(31.20–39.08) 34.77 ± 0.90 0.599
 GLB (g/L) 28.81 ± 0.62 29.20(26.20–33.48) 30.81 ± 0.85 0.110
 Albumin / GLB 1.14(1.04–1.44) 1.19(1.00–1.37) 1.18 ± 0.05 0.791
 GGT (U/L) 24.50(15.00–50.00) 24.00(16.00–43.50) 26.50(17.00–60.00) 0.699
 ALP (U/L) 83.50(63.50–96.25) 86.00(68.00–108.00) 88.00(63.75–110.00) 0.480
 TBA (μmol/L) 4.35(2.68–6.63) 3.80(2.10–6.50) 3.50(1.78–8.90) 0.350
 SOD (U/L) 135.54 ± 4.34 127.25 ± 1.88 136.35 ± 4.78 0.200
 GLU(mmol/L) 6.56(5.25–7.99) 5.05(4.50–6.47) 6.62(4.87–9.37) < 0.001
Renal function
 BUN (mmol/L) 21.60(15.10–26.05) 16.75(11.30–23.25) 15.65(10.55–22.83) 0.002
 CREA (μmol/L) 688.69 ± 44.73 479.50(253.60–765.00) 593.93 ± 61.47 0.005
 Uric acid (μmol/L) 438.17 ± 16.93 417.80(333.98–529.58) 443.67 ± 26.47 0.778
 CO2 (mmol/L) 21.45 ± 0.62 22.39 ± 0.22 22.10 ± 0.74 0.419
 Cystatin C (mg/L) 4.08(3.17–5.24) 3.78(2.85–5.31) 4.31 ± 0.36 0.258
 eGFR (mL/min/1.73m2) 7.13(4.63–15.01) 8.94(5.36–18.45) 7.10(5.29–22.04) 0.147
Serum lipids
 TC (mmol/L) 3.55 ± 0.12 3.80(3.20–4.68) 3.70(3.25–4.85) 0.009
 TG (mmol/L) 1.56(0.79–1.73) 1.38(1.01–2.04) 1.99(1.39–2.58) < 0.001
 HDL-C (mmol/L) 0.93 ± 0.03 0.90(0.72–1.11) 0.84 ± 0.06 0.088
 LDL-C (mmol/L) 1.86 ± 0.07 1.97(1.62–2.62) 2.15 ± 0.12 0.009
 ApoA1 (g/L) 0.99 ± 0.04 1.00(0.84–1.19) 0.95 ± 0.08 0.243
 ApoB (g/L) 0.58 ± 0.03 0.67(0.55–0.80) 0.72 ± 0.05 0.018
 Lp(a) (mg/L) 171.35(79.48–349.40) 152.35(73.25–316.03) 125.45(63.48–340.75) 0.420
 FFA (μmol/L) 85.90(55.43–107.07) 348.31(247.31–480.56) 964.61(848.95–1283.06) < 0.001
 PLIP (mmol/L) 1.96 ± 0.59 2.06(1.82–2.36) 2.10(1.82–2.67) 0.017
Serum electrolytes
 K+ (mmol/L) 4.47 ± 0.10 4.32(3.90–4.91) 4.25 ± 0.14 0.178
 Na+ (mmol/L) 138.20(135.50–141.03) 138.75(136.50–140.80) 136.75(133.93–139.78) 0.020
 Cl (mmol/L) 104.20(101.53–109.15) 104.64 ± 0.27 100.72 ± 0.85 < 0.001
 Ca2+ (mmol/L) 2.08 ± 0.03 2.17(2.00–2.32) 2.18 ± 0.05 0.050
 Mg2+ (mmol/L) 0.96 ± 0.02 0.95(0.85–1.05) 0.97 ± 0.04 0.939
 Phosphate (mmol/L) 1.53(1.23–1.96) 1.46(1.15–1.91) 1.56(0.98–1.96) 0.454
  1. ApoA1 apolipoprotein A1, ApoB apolipoprotein B, FFA free fatty acid