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Table 2 The differences of clinical parameters across three groups dividing by serum FFAs

From: Evaluation of serum free fatty acids in chronic renal failure: evidence from a rare case with undetectable serum free fatty acids and population data

Parameter

FFA-reduced group (n = 78)

FFA-normal group (n = 450)

FFA-increased group (n = 46)

P-value

Age (year)

59.3± 1.9

66.0(52.0–76.0)

66.4 ± 2.2

0.053

Liver function

 ALT (U/L)

16.50(10.00–25.25)

13.00(8.00–20.00)

12.00(7.75–19.25)

0.091

 AST (U/L)

18.00(12.75–25.25)

18.00(14.00–25.00)

22.00(15.5–33.25)

0.078

 AST/ALT

1.17(0.81–1.68)

1.38(1.00–1.75)

1.87(1.00–2.86)

0.001

 TBIL (μmol/L)

8.15(6.70–10.48)

8.50(7.10–11.30)

10.45(8.50–15.65)

< 0.001

 DBIL (μmol/L)

1.35(1.00–2.10)

1.50(1.10–2.20)

2.25(1.58–4.15)

< 0.001

 UBIL (μmol/L)

6.80(5.70–8.53)

7.00(5.83–8.90)

8.05(6.93–12.15)

0.004

 TP (g/L)

62.25(59.70–68.60)

64.50(58.90–70.10)

65.58 ± 1.12

0.169

 Albumin (g/L)

33.94 ± 0.63

34.80(31.20–39.08)

34.77 ± 0.90

0.599

 GLB (g/L)

28.81 ± 0.62

29.20(26.20–33.48)

30.81 ± 0.85

0.110

 Albumin / GLB

1.14(1.04–1.44)

1.19(1.00–1.37)

1.18 ± 0.05

0.791

 GGT (U/L)

24.50(15.00–50.00)

24.00(16.00–43.50)

26.50(17.00–60.00)

0.699

 ALP (U/L)

83.50(63.50–96.25)

86.00(68.00–108.00)

88.00(63.75–110.00)

0.480

 TBA (μmol/L)

4.35(2.68–6.63)

3.80(2.10–6.50)

3.50(1.78–8.90)

0.350

 SOD (U/L)

135.54 ± 4.34

127.25 ± 1.88

136.35 ± 4.78

0.200

 GLU(mmol/L)

6.56(5.25–7.99)

5.05(4.50–6.47)

6.62(4.87–9.37)

< 0.001

Renal function

 BUN (mmol/L)

21.60(15.10–26.05)

16.75(11.30–23.25)

15.65(10.55–22.83)

0.002

 CREA (μmol/L)

688.69 ± 44.73

479.50(253.60–765.00)

593.93 ± 61.47

0.005

 Uric acid (μmol/L)

438.17 ± 16.93

417.80(333.98–529.58)

443.67 ± 26.47

0.778

 CO2 (mmol/L)

21.45 ± 0.62

22.39 ± 0.22

22.10 ± 0.74

0.419

 Cystatin C (mg/L)

4.08(3.17–5.24)

3.78(2.85–5.31)

4.31 ± 0.36

0.258

 eGFR (mL/min/1.73m2)

7.13(4.63–15.01)

8.94(5.36–18.45)

7.10(5.29–22.04)

0.147

Serum lipids

 TC (mmol/L)

3.55 ± 0.12

3.80(3.20–4.68)

3.70(3.25–4.85)

0.009

 TG (mmol/L)

1.56(0.79–1.73)

1.38(1.01–2.04)

1.99(1.39–2.58)

< 0.001

 HDL-C (mmol/L)

0.93 ± 0.03

0.90(0.72–1.11)

0.84 ± 0.06

0.088

 LDL-C (mmol/L)

1.86 ± 0.07

1.97(1.62–2.62)

2.15 ± 0.12

0.009

 ApoA1 (g/L)

0.99 ± 0.04

1.00(0.84–1.19)

0.95 ± 0.08

0.243

 ApoB (g/L)

0.58 ± 0.03

0.67(0.55–0.80)

0.72 ± 0.05

0.018

 Lp(a) (mg/L)

171.35(79.48–349.40)

152.35(73.25–316.03)

125.45(63.48–340.75)

0.420

 FFA (μmol/L)

85.90(55.43–107.07)

348.31(247.31–480.56)

964.61(848.95–1283.06)

< 0.001

 PLIP (mmol/L)

1.96 ± 0.59

2.06(1.82–2.36)

2.10(1.82–2.67)

0.017

Serum electrolytes

 K+ (mmol/L)

4.47 ± 0.10

4.32(3.90–4.91)

4.25 ± 0.14

0.178

 Na+ (mmol/L)

138.20(135.50–141.03)

138.75(136.50–140.80)

136.75(133.93–139.78)

0.020

 Cl (mmol/L)

104.20(101.53–109.15)

104.64 ± 0.27

100.72 ± 0.85

< 0.001

 Ca2+ (mmol/L)

2.08 ± 0.03

2.17(2.00–2.32)

2.18 ± 0.05

0.050

 Mg2+ (mmol/L)

0.96 ± 0.02

0.95(0.85–1.05)

0.97 ± 0.04

0.939

 Phosphate (mmol/L)

1.53(1.23–1.96)

1.46(1.15–1.91)

1.56(0.98–1.96)

0.454

  1. ApoA1 apolipoprotein A1, ApoB apolipoprotein B, FFA free fatty acid