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Table 2 Regression analyses of age-adjusted ∆apoB-containing lipoproteins vs. ∆BMI over clinic visits. SI units

From: Effects of weight change on apolipoprotein B-containing emerging atherosclerotic cardiovascular disease (ASCVD) risk factors

Dependent variable Male Female Sex dif-ference (P) Sample (N)
Slope ± SE Signif-icance Slope ± SE Signi-ficance Male/female
∆Triglyceridesa
 1st followup 0.0358 ± 0.0049 2.0 × 10−13 0.0304 ± 0.0029 < 10−16 0.33 14690/17977
 2nd followup 0.0308 ± 0.0076 5.1 × 10− 5 0.033 ± 0.0053 3.4 × 10−10 0.77 5109/5893
 3rd followup 0.0147 ± 0.0115 0.20 0.0315 ± 0.005 3.0 × 10−10 0.16 2334/2372
∆Log triglycerides
 1st followup 0.019 ± 0.002 < 10−16 0.019 ± 0.001 < 10− 16 0.96 14690/17977
 2nd followup 0.024 ± 0.003 < 10−16 0.025 ± 0.002 < 10−16 0.89 5109/5893
 3rd followup 0.020 ± 0.004 7.9 × 10−8 0.022 ± 0.003 2.7 × 10−15 0.57 2334/2372
∆Apo Bb
 1st followup 0.0053 ± 0.0010 7.9 × 10− 8 0.0073 ± 0.0009 2.2 × 10−16 0.12 13384/16458
 2nd followup 0.005 ± 0.0017 0.003 0.0072 ± 0.0015 9.6 × 10−7 0.29 4483/5231
 3rd followup 0.0075 ± 0.0028 0.007 0.0067 ± 0.0023 0.003 0.85 1925/1973
∆nonHDL-cholesterola
 1st followup 0.0238 ± 0.0041 7.9 × 10−9 0.0330 ± 0.0037 < 10− 16 0.07 12471/15149
 2nd followup 0.0254 ± 0.0068 0.0002 0.0282 ± 0.0059 2.0 × 10−6 0.72 4323/4860
 3rd followup 0.0235 ± 0.0089 0.008 0.0267 ± 0.009 0.003 0.81 1974/1979
∆LDL-cholesterol directa
 1st followup 0.0128 ± 0.0034 0.0002 0.0232 ± 0.0031 1.2 × 10−13 0.02 14349/17625
 2nd followup 0.0093 ± 0.0058 0.11 0.0202 ± 0.0051 7.5 × 10−5 0.14 4985/5792
 3rd followup 0.0134 ± 0.0078 0.09 0.0235 ± 0.0075 0.002 0.34 2287/2331
∆LDL-cholesterol indirecta
 1st followup 0.0084 ± 0.0034 0.01 0.0186 ± 0.0031 1.6 × 10−9 0.02 14238/17455
 2nd followup 0.0048 ± 0.0059 0.41 0.0134 ± 0.0051 0.008 0.22 4954/5700
 3rd followup 0.0139 ± 0.0077 0.07 0.0198 ± 0.0076 0.009 0.56 2282/2307
∆sdLDL-cholesterola
 1st followup 0.0125 ± 0.0015 2.2 × 10−16 0.0128 ± 0.0012 < 10− 16 0.85 13668/16875
 2nd followup 0.0109 ± 0.0025 8.2 × 10−6 0.0144 ± 0.0019 8.4 × 10−15 0.21 4721/5524
 3rd followup 0.0121 ± 0.0033 0.0003 0.0123 ± 0.0027 4.6 × 10−6 0.92 2185/2235
∆lbLDL-cholesterol a
 1st followup 0.0007 ± 0.0026 0.78 0.0098 ± 0.0024 3.9 × 10−5 0.008 13518/16727
 2nd followup −0.0005 ± 0.0044 0.90 0.0055 ± 0.0039 0.16 0.27 4680/5475
 3rd followup 0.0021 ± 0.0059 0.72 0.0114 ± 0.0057 0.05 0.25 2174/2210
∆%sdLDL-cholesterolc
 1st followup 0.296 ± 0.035 < 10−16 0.221 ± 0.023 < 10− 16 0.06 10605/13757
 2nd followup 0.294 ± 0.06 8.2 × 10−7 0.259 ± 0.038 6.4 × 10−12 0.63 3429/4229
 3rd followup 0.389 ± 0.098 6.9 × 10−5 0.196 ± 0.056 0.0004 0.07 1438/1522
∆LDL-particle numbera
 1st followup 0.0128 ± 0.0024 2.1 × 10− 7 0.0114 ± 0.0022 3.2 × 10− 7 0.69 7408/9025
 2nd followup 0.0100 ± 0.0036 0.005 0.0109 ± 0.0034 0.002 0.81 2600/3004
 3rd followup 0.0122 ± 0.0046 0.008 0.0117 ± 0.0048 0.02 0.92 1177/1289
∆Lp(a)d
 1st followup −0.0206 ± 0.0064 0.001 −0.0010 ± 0.0030 0.75 0.009 13126/16094
 2nd followup −0.0257 ± 0.0087 0.003 −0.0121 ± 0.0047 0.01 0.15 4587/5277
 3rd followup −0.029 ± 0.0094 0.002 −0.0092 ± 0.0064 0.15 0.19 2138/2169
∆Log Lp(a)d
 1st followup −0.002 ± 0.001 4.7 × 10−5 0.000 ± 0.000 0.94 0.003 13113/16077
 2nd followup −0.004 ± 0.001 8.6 × 10−6 − 0.002 ± 0.001 0.02 0.06 4586/5273
 3rd followup −0.004 ± 0.001 0.004 −0.002 ± 0.001 0.11 0.20 2138/2169
  1. a ∆mmol/L per ∆kg/m2; b ∆g/L per ∆kg/m2; c∆% per ∆kg/m2; d∆μmol/L per ∆kg/m2