Lipids in Health and Disease

Table 2 Regression analyses of age-adjusted ∆apoB-containing lipoproteins vs. ∆BMI over clinic visits. SI units

From: Effects of weight change on apolipoprotein B-containing emerging atherosclerotic cardiovascular disease (ASCVD) risk factors

Dependent variable	Male		Female		Sex dif-ference (P)	Sample (N)
Dependent variable	Slope ± SE	Signif-icance	Slope ± SE	Signi-ficance	Sex dif-ference (P)	Male/female
∆Triglycerides^a
1st followup	0.0358 ± 0.0049	2.0 × 10⁻¹³	0.0304 ± 0.0029	< 10⁻¹⁶	0.33	14690/17977
2nd followup	0.0308 ± 0.0076	5.1 × 10^− 5	0.033 ± 0.0053	3.4 × 10⁻¹⁰	0.77	5109/5893
3rd followup	0.0147 ± 0.0115	0.20	0.0315 ± 0.005	3.0 × 10⁻¹⁰	0.16	2334/2372
∆Log triglycerides
1st followup	0.019 ± 0.002	< 10⁻¹⁶	0.019 ± 0.001	< 10^− 16	0.96	14690/17977
2nd followup	0.024 ± 0.003	< 10⁻¹⁶	0.025 ± 0.002	< 10⁻¹⁶	0.89	5109/5893
3rd followup	0.020 ± 0.004	7.9 × 10⁻⁸	0.022 ± 0.003	2.7 × 10⁻¹⁵	0.57	2334/2372
∆Apo B^b
1st followup	0.0053 ± 0.0010	7.9 × 10^− 8	0.0073 ± 0.0009	2.2 × 10⁻¹⁶	0.12	13384/16458
2nd followup	0.005 ± 0.0017	0.003	0.0072 ± 0.0015	9.6 × 10⁻⁷	0.29	4483/5231
3rd followup	0.0075 ± 0.0028	0.007	0.0067 ± 0.0023	0.003	0.85	1925/1973
∆nonHDL-cholesterol^a
1st followup	0.0238 ± 0.0041	7.9 × 10⁻⁹	0.0330 ± 0.0037	< 10^− 16	0.07	12471/15149
2nd followup	0.0254 ± 0.0068	0.0002	0.0282 ± 0.0059	2.0 × 10⁻⁶	0.72	4323/4860
3rd followup	0.0235 ± 0.0089	0.008	0.0267 ± 0.009	0.003	0.81	1974/1979
∆LDL-cholesterol direct^a
1st followup	0.0128 ± 0.0034	0.0002	0.0232 ± 0.0031	1.2 × 10⁻¹³	0.02	14349/17625
2nd followup	0.0093 ± 0.0058	0.11	0.0202 ± 0.0051	7.5 × 10⁻⁵	0.14	4985/5792
3rd followup	0.0134 ± 0.0078	0.09	0.0235 ± 0.0075	0.002	0.34	2287/2331
∆LDL-cholesterol indirect^a
1st followup	0.0084 ± 0.0034	0.01	0.0186 ± 0.0031	1.6 × 10⁻⁹	0.02	14238/17455
2nd followup	0.0048 ± 0.0059	0.41	0.0134 ± 0.0051	0.008	0.22	4954/5700
3rd followup	0.0139 ± 0.0077	0.07	0.0198 ± 0.0076	0.009	0.56	2282/2307
∆sdLDL-cholesterol^a
1st followup	0.0125 ± 0.0015	2.2 × 10⁻¹⁶	0.0128 ± 0.0012	< 10^− 16	0.85	13668/16875
2nd followup	0.0109 ± 0.0025	8.2 × 10⁻⁶	0.0144 ± 0.0019	8.4 × 10⁻¹⁵	0.21	4721/5524
3rd followup	0.0121 ± 0.0033	0.0003	0.0123 ± 0.0027	4.6 × 10⁻⁶	0.92	2185/2235
∆lbLDL-cholesterol ^a
1st followup	0.0007 ± 0.0026	0.78	0.0098 ± 0.0024	3.9 × 10⁻⁵	0.008	13518/16727
2nd followup	−0.0005 ± 0.0044	0.90	0.0055 ± 0.0039	0.16	0.27	4680/5475
3rd followup	0.0021 ± 0.0059	0.72	0.0114 ± 0.0057	0.05	0.25	2174/2210
∆%sdLDL-cholesterol^c
1st followup	0.296 ± 0.035	< 10⁻¹⁶	0.221 ± 0.023	< 10^− 16	0.06	10605/13757
2nd followup	0.294 ± 0.06	8.2 × 10⁻⁷	0.259 ± 0.038	6.4 × 10⁻¹²	0.63	3429/4229
3rd followup	0.389 ± 0.098	6.9 × 10⁻⁵	0.196 ± 0.056	0.0004	0.07	1438/1522
∆LDL-particle number^a
1st followup	0.0128 ± 0.0024	2.1 × 10^− 7	0.0114 ± 0.0022	3.2 × 10^− 7	0.69	7408/9025
2nd followup	0.0100 ± 0.0036	0.005	0.0109 ± 0.0034	0.002	0.81	2600/3004
3rd followup	0.0122 ± 0.0046	0.008	0.0117 ± 0.0048	0.02	0.92	1177/1289
∆Lp(a)^d
1st followup	−0.0206 ± 0.0064	0.001	−0.0010 ± 0.0030	0.75	0.009	13126/16094
2nd followup	−0.0257 ± 0.0087	0.003	−0.0121 ± 0.0047	0.01	0.15	4587/5277
3rd followup	−0.029 ± 0.0094	0.002	−0.0092 ± 0.0064	0.15	0.19	2138/2169
∆Log Lp(a)^d
1st followup	−0.002 ± 0.001	4.7 × 10⁻⁵	0.000 ± 0.000	0.94	0.003	13113/16077
2nd followup	−0.004 ± 0.001	8.6 × 10⁻⁶	− 0.002 ± 0.001	0.02	0.06	4586/5273
3rd followup	−0.004 ± 0.001	0.004	−0.002 ± 0.001	0.11	0.20	2138/2169

^a ∆mmol/L per ∆kg/m²; ^b ∆g/L per ∆kg/m²; ^c∆% per ∆kg/m²; ^d∆μmol/L per ∆kg/m²

Back to article page

ISSN: 1476-511X

Contact us

General enquiries: journalsubmissions@springernature.com