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Table 3 Regression analyses of age- and sex-adjusted ∆apoB-containing lipoproteins vs. ∆BMI over clinic visits, SI units

From: Effects of weight change on apolipoprotein B-containing emerging atherosclerotic cardiovascular disease (ASCVD) risk factors

  Adjusted for age and sex only Additional adjustment for ∆triglycerides and ∆LDL-cholesterol Sample (N)
Dependent variable Slope ± SE Significance Slope ± SE Significance  
∆Apo Bb
 1st followup 0.0064 ± 0.0007 < 10− 16 0.001 ± 0.0003 0.0008 29342
 2nd followup 0.0063 ± 0.0011 1.9 × 10−8 0.0016 ± 0.0005 0.0006 9642
 3rd followup 0.007 ± 0.0017 5.8 × 10−5 0.001 ± 0.0007 0.16 3877
∆nonHDL-cholesterol a
 1st followup 0.0289 ± 0.0027 < 10−16 0.0019 ± 0.0009 0.03 27613
 2nd followup 0.027 ± 0.0045 1.5 × 10−9 0.0058 ± 0.0015 0.0001 9180
 3rd followup 0.0252 ± 0.0063 6.8 × 10−5 0.0088 ± 0.0022 6.3 × 10− 5 3952
∆sdLDL-cholesterol a
 1st followup 0.0008 ± 0.0001 < 10−16 0.0001 ± 0.0000 1.6 × 10−11 29988
 2nd followup 0.0007 ± 0.0001 < 10−16 0.0002 ± 0.0001 1.5 × 10−11 10164
 3rd followup 0.0006 ± 0.0002 6.6 × 10−9 0.0002 ± 0.0001 0.0003 4396
∆lbLDL-cholesterol a
 1st followup 0.0059 ± 0.0018 0.0009 −0.0041 ± 0.0006 3.4 × 10−13 30056
 2nd followup 0.0029 ± 0.0029 0.33 −0.0059 ± 0.0009 3.8 × 10−11 10124
 3rd followup 0.0073 ± 0.0041 0.08 −0.0052 ± 0.0012 3.2 × 10−15 4376
∆%sdLDL-cholesterolc
 1st followup 0.254 ± 0.02 < 10−16 0.151 ± 0.018 < 10−16 24274
 2nd followup 0.274 ± 0.034 4.4 × 10−16 0.186 ± 0.03 3.8 × 10−10 7633
 3rd followup 0.27 ± 0.053 2.9 × 10−7 0.218 ± 0.049 8.2 × 10−6 2952
∆LDL-particle numbera
 1st followup 0.0121 ± 0.0017 2.9 × 10−13 0.0032 ± 0.0010 0.001 16135
 2nd followup 0.0105 ± 0.0025 2.6 × 10−5 0.0039 ± 0.0015 0.01 5554
 3rd followup 0.0119 ± 0.0033 0.0003 0.0037 ± 0.0022 0.10 2452
∆Lp(a)d
 1st followup −0.0059 ± 0.0021 0.005 −0.0091 ± 0.0021 1.2 × 10−5 28096
 2nd followup −0.0163 ± 0.0033 7.8 × 10−7 − 0.018 ± 0.0033 5.3 × 10−8 9673
 3rd followup −0.0142 ± 0.0045 0.002 −0.0155 ± 0.0045 0.0006 4264
∆Log Lp(a)
 1st followup −0.001 ± 0 0.005 −0.002 ± 0 9.0 × 10−6 28096
 2nd followup −0.003 ± 0.001 2.9 × 10− 6 −0.003 ± 0.001 2.2 × 10−7 9673
 3rd followup −0.003 ± 0.001 0.002 −0.003 ± 0.001 0.0006 4264
∆Triglyceridesa
 1st followup 0.0328 ± 0.0027 < 10−16    32674
 2nd followup 0.032 ± 0.0045 7.5 × 10−13    11001
 3rd followup 0.0241 ± 0.006 6.1 × 10−5    4706
∆LDL-cholesterola
 1st followup 0.0186 ± 0.0023 6.7 × 10−16    31981
 2nd followup 0.0155 ± 0.0038 5.3 × 10−5    10776
 3rd followup 0.019 ± 0.0054 0.0004    4618
  1. a ∆mmol/L per ∆kg/m2; b ∆g/L per ∆kg/m2; c∆% per ∆kg/m2; d∆μmol/L per ∆kg/m2