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Table 1 Patient demographics, characteristics, and baseline comorbidities [14]

From: Long-term statin persistence is poor among high-risk patients with dyslipidemia: a real-world administrative claims analysis

 

Elevated-TG Cohorta

(n = 23,181)

Comparator Cohorta

(n = 23,181)

P Value

Age, mean (SD), years

62.2 (9.6)

62.6 (9.9)

<0.001

Female, n (%)

11,518 (49.7)

11,467 (49.5)

0.244

Insurance type, n (%)

 Commercial

15,823 (68.3)

15,855 (68.4)

0.461

 Medicare

7358 (31.7)

7326 (31.6)

0.461

Duration of follow-up, mean (SD), months

41.4 (23.7)

42.5 (23.9)

<0.001

Baselineb lipid profile, mean (SD), mg/dL

 TG

220.31 (77.4)

97.9 (28.9)

<0.001

 LDL-C

104.6 (41.1)

100.9 (35.0)

<0.001

 HDL-C

42.3 (10.2)

55.1 (12.2)

<0.001

 Total cholesterol

190.2 (46.6)

175.4 (38.8)

<0.001

 Non-HDL-Cc

147.9 (44.2)

120.4 (36.5)

<0.001

Baseline comorbidities, n (%)

 Diabetes

19,392 (83.7)

19,478 (84.0)

0.017

 ASCVD

6915 (29.8)

6800 (29.3)

0.009

 MI

495 (2.1)

411 (1.8)

0.003

 Stroke

750 (3.2)

674 (2.9)

0.005

 Angina

1225 (5.3)

1179 (5.1)

0.284

 Coronary revascularization

600 (2.6)

506 (2.2)

0.002

 Peripheral artery disease

3384 (14.6)

3317 (14.3)

0.104

 Heart failure

1258 (5.4)

1088 (4.7)

<0.001

 Atrial fibrillation

1133 (4.9)

989 (4.3)

0.001

 Hypertension

18,346 (79.1)

18,375 (79.3)

0.462

 Renal disease

2832 (12.2)

2782 (12.0)

0.196

  1. Rao-Scott test was used for binary measures. Robust standard errors were used for continuous measures
  2. aElevated TG ≥150 mg/dL and matched comparator with TG < 150 mg/dL and HDL-C > 40 mg/dL
  3. bBaseline period excludes index date
  4. cCalculated by subtracting HDL-C result from total cholesterol. This value was not calculated unless patients had both HDL-C and total cholesterol laboratory result in period
  5. ASCVD atherosclerotic cardiovascular disease, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, MI myocardial infarction, non-HDL-C non-high-density lipoprotein cholesterol, SD standard deviation, TG triglycerides