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Table 10 Statin persistence over time in patient subgroup with peripheral artery disease

From: Long-term statin persistence is poor among high-risk patients with dyslipidemia: a real-world administrative claims analysis

Cohort

 

Time (Years)

0.5

1

2

3

4

5

A) Elevated-TG analysis

       

Study population with baseline PAD (1)

Proportion

0.6327

0.4965

0.3681

0.2866

0.2444

0.2110

At risk

2117

1427

835

547

341

233

Study population with no baseline PAD (2)

Proportion

0.6003

0.4668

0.3338

0.2649

0.2168

0.1841

At risk

11,842

7845

4428

2901

1693

1138

Comparison group with baseline PAD (3)

Proportion

0.6182

0.4960

0.3653

0.2994

0.2493

0.2130

At risk

2022

1412

825

578

331

229

Comparison group with no baseline PAD (4)

Proportion

0.5947

0.4682

0.3406

0.2710

0.2229

0.1903

At risk

11,774

7984

4589

3059

1787

1206

Clustered P values for between-group comparisons in the elevated-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

< 0.001

0.911

0.001

< 0.001

0.431

0.003

B) High-TG analysis

Study population with baseline PAD (1)

Proportion

0.6279

0.4780

0.3465

0.2677

0.2216

0.1967

At risk

966

622

364

236

144

105

Study population with no baseline PAD (2)

Proportion

0.5849

0.4529

0.3199

0.2522

0.2015

0.1699

At risk

5499

3619

2007

1309

755

500

Comparison group with baseline PAD (3)

Proportion

0.6067

0.4925

0.3619

0.2921

0.2418

0.2066

At risk

925

655

377

259

146

103

Comparison group with no baseline PAD (4)

Proportion

0.5841

0.4543

0.3283

0.2632

0.2203

0.1903

At risk

5503

3673

2097

1398

827

547

Clustered P values for between-group comparisons in the high-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.016

0.680

0.107

0.004

0.121

0.037

  1. Kaplan-Meier analysis. Clustered P values were calculated using Cox proportional hazard model with cohort as independent variable. Study population is the elevated-TG cohort (TG ≥150 mg/dL) and high-TG subcohort and their propensity score matched comparators with TG < 150 mg/dL and HDL-C > 40 mg/dL
  2. HDL-C high-density lipoprotein cholesterol, PAD peripheral artery disease, TG triglycerides
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Lipids in Health and Disease

ISSN: 1476-511X