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Table 11 Statin persistence over time in patient subgroup with renal disease

From: Long-term statin persistence is poor among high-risk patients with dyslipidemia: a real-world administrative claims analysis

Cohort

 

Time (Years)

0.5

1

2

3

4

5

A) Elevated-TG analysis

       

Study population with baseline renal disease (1)

Proportion

0.6321

0.4955

0.3556

0.2743

0.2256

0.1941

At risk

1769

1156

633

406

249

172

Study population with no baseline renal disease (2)

Proportion

0.6012

0.4677

0.3365

0.2671

0.2201

0.1872

At risk

12,190

8116

4630

3042

1785

1199

Comparison group with baseline renal disease (3)

Proportion

0.6298

0.4967

0.3722

0.2945

0.2411

0.2118

At risk

1731

1170

673

456

278

190

Comparison group with no baseline renal disease (4)

Proportion

0.5938

0.4689

0.3404

0.2724

0.2247

0.1911

At risk

12,065

8226

4741

3181

1840

1245

Clustered P values for between-group comparisons in the elevated-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.054

0.252

0.070

<0.001

0.775

0.001

B) High-TG analysis

Study population with baseline renal disease (1)

Proportion

0.6332

0.4797

0.3384

0.2602

0.2041

0.1741

At risk

824

511

268

175

102

70

Study population with no baseline renal disease (2)

Proportion

0.5853

0.4533

0.3216

0.2535

0.2043

0.1736

At risk

5641

3730

2103

1370

797

535

Comparison group with baseline renal disease (3)

Proportion

0.6305

0.4963

0.3637

0.2795

0.2374

0.2118

At risk

819

554

319

210

135

92

Comparison group with no baseline renal disease (4)

Proportion

0.5814

0.4547

0.3288

0.2656

0.2213

0.1899

At risk

5609

3774

2155

1447

838

558

Clustered P values for between-group comparisons in the high-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.130

0.118

0.309

<0.001

0.271

0.003

  1. Kaplan-Meier analysis. Clustered P values were calculated using Cox proportional hazard model with cohort as independent variable. Study population is the elevated-TG cohort (TG ≥150 mg/dL) and high-TG subcohort and their propensity score matched comparators with TG < 150 mg/dL and HDL-C > 40 mg/dL
  2. HDL-C high-density lipoprotein cholesterol, TG triglycerides
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Lipids in Health and Disease

ISSN: 1476-511X