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Table 7 Statin persistence over time in patient subgroup with diabetes

From: Long-term statin persistence is poor among high-risk patients with dyslipidemia: a real-world administrative claims analysis

Cohort

 

Time (Years)

0.5

1

2

3

4

5

A) Elevated-TG analysis

Study population with baseline diabetes (1)

Proportion

0.6028

0.4692

0.3369

0.2653

0.2173

0.1840

At risk

11,644

7716

4369

2851

1663

1113

Study population with no baseline diabetes (2)

Proportion

0.6163

0.4811

0.3487

0.2821

0.2391

0.2085

At risk

2315

1556

894

597

371

258

Comparison group with baseline diabetes (3)

Proportion

0.5950

0.4684

0.3405

0.2710

0.2236

0.1904

At risk

11,537

7855

4519

3010

1762

1194

Comparison group with no baseline diabetes (4)

Proportion

0.6144

0.4920

0.3633

0.2966

0.2432

0.2105

At risk

2259

1541

895

627

356

241

Clustered P values for between-group comparisons in the elevated-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.029

0.723

0.001

0.045

0.376

0.002

B) High-TG analysis

Study population with baseline diabetes (1)

Proportion

0.5881

0.4551

0.3232

0.2532

0.2021

0.1701

At risk

5463

3600

2013

1309

754

503

Study population with no baseline diabetes (2)

Proportion

0.6074

0.4642

0.3262

0.2610

0.2171

0.1944

At risk

1002

641

358

236

145

102

Comparison group with baseline diabetes (3)

Proportion

0.5845

0.4552

0.3281

0.2639

0.2211

0.1909

At risk

5460

3671

2094

1403

838

563

Comparison group with no baseline diabetes (4)

Proportion

0.6036

0.4854

0.3619

0.2868

0.2351

0.2021

At risk

968

657

380

254

135

87

Clustered P values for between-group comparisons in the high-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.259

0.246

0.005

0.572

0.168

0.025

  1. Kaplan-Meier analysis. Clustered P values were calculated using Cox proportional hazard model with cohort as independent variable. Study population is the elevated-TG cohort (TG ≥150 mg/dL) and high-TG subcohort and their propensity score matched comparators with TG < 150 mg/dL and HDL-C > 40 mg/dL
  2. HDL-C high-density lipoprotein cholesterol, TG triglycerides
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Lipids in Health and Disease

ISSN: 1476-511X