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Table 8 Statin persistence over time in patient subgroup with revascularization

From: Long-term statin persistence is poor among high-risk patients with dyslipidemia: a real-world administrative claims analysis

Cohort

 

Time (Years)

0.5

1

2

3

4

5

A) Elevated-TG analysis

Study population with baseline revascularization (1)

Proportion

0.6620

0.5162

0.3687

0.3120

0.2424

0.2049

At risk

393

257

136

88

40

21

Study population with no baseline revascularization (2)

Proportion

0.6035

0.4699

0.3380

0.2670

0.2203

0.1876

At risk

13,566

9015

5127

3360

1994

1350

Comparison group with baseline revascularization (3)

Proportion

0.6697

0.5362

0.3777

0.3076

0.2570

0.2124

At risk

336

229

122

85

52

35

Comparison group with no baseline revascularization (4)

Proportion

0.5965

0.4708

0.3434

0.2743

0.2260

0.1931

At risk

13,460

9167

5292

3552

2066

1400

Clustered P values for between-group comparisons in the elevated-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.051

0.336

0.062

0.002

0.580

0.003

B) High-TG analysis

Study population with baseline revascularization (1)

Proportion

0.6526

0.5026

0.3474

0.2920

0.2177

0.1910

At risk

191

120

61

42

19

9

Study population with no baseline revascularization (2)

Proportion

0.5893

0.4552

0.3230

0.2534

0.2040

0.1734

At risk

6274

4121

2310

1503

880

596

Comparison group with baseline revascularization (3)

Proportion

0.6620

0.5094

0.3659

0.2928

0.2560

0.2058

At risk

141

93

53

36

24

16

Comparison group with no baseline revascularization (4)

Proportion

0.5858

0.4587

0.3324

0.2668

0.2226

0.1923

At risk

6287

4235

2421

1621

949

634

Clustered P values for between-group comparisons in the high-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.153

0.483

0.263

0.039

0.124

0.075

  1. Kaplan-Meier analysis. Clustered P values were calculated using Cox proportional hazard model with cohort as independent variable. Study population is the elevated-TG cohort (TG ≥150 mg/dL) and high-TG subcohort and their propensity score matched comparators with TG < 150 mg/dL and HDL-C > 40 mg/dL
  2. HDL-C high-density lipoprotein cholesterol, TG triglycerides