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Table 9 Statin persistence over time in patient subgroup with heart failure

From: Long-term statin persistence is poor among high-risk patients with dyslipidemia: a real-world administrative claims analysis

Cohort

 

Time (Years)

0.5

1

2

3

4

5

A) Elevated-TG analysis

       

Study population with baseline CHF (1)

Proportion

0.6407

0.4965

0.3838

0.2977

0.2467

0.2170

At risk

781

498

297

185

109

78

Study population with no baseline CHF (2)

Proportion

0.6030

0.4697

0.3364

0.2664

0.2194

0.1865

At risk

13,178

8774

4966

3263

1925

1293

Comparison group with baseline CHF (3)

Proportion

0.6286

0.4885

0.3642

0.2925

0.2474

0.2119

At risk

667

435

248

160

92

64

Comparison group with no

Proportion

0.5966

0.4714

0.3432

0.2742

0.2257

0.1927

baseline CHF (4)

At risk

13,129

8961

5166

3477

2026

1371

Clustered P values for between-group comparisons in the elevated-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.010

0.777

0.019

0.045

0.426

0.071

B) High-TG analysis

Study population with baseline CHF (1)

Proportion

0.6275

0.4813

0.3888

0.3019

0.2440

0.2235

At risk

378

235

147

89

50

39

Study population with no baseline CHF (2)

Proportion

0.5888

0.4550

0.3200

0.2517

0.2021

0.1711

At risk

6087

4006

2224

1456

849

566

Comparison group with baseline CHF (3)

Proportion

0.5962

0.4514

0.3563

0.2788

0.2360

0.1929

At risk

303

195

118

76

42

27

Comparison group with no baseline CHF (4)

Proportion

0.5869

0.4600

0.3319

0.2667

0.2227

0.1926

At risk

6125

4133

2356

1581

931

623

Clustered P values for between-group comparisons in the high-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.026

0.336

0.093

0.419

0.059

0.761

  1. Kaplan-Meier analysis. Clustered P values were calculated using Cox proportional hazard model with cohort as independent variable. Study population is the elevated-TG cohort (TG ≥150 mg/dL) and high-TG subcohort and their propensity score matched comparators with TG < 150 mg/dL and HDL-C > 40 mg/dL
  2. CHF congestive heart failure, HDL-C high-density lipoprotein cholesterol, TG triglycerides