subgroup | LDL-C < 3.4 mmol/L | 3.4 mmol/L ≤ LDL-C < 4.1 mmol/L | LDLC ≥4.1 mmol/L | ||||||
---|---|---|---|---|---|---|---|---|---|
OR(95%CIs) | P-value | P-interaction | OR(95%CIs) | P-value | P-interaction | OR(95%CIs) | P-value | P-interaction | |
Age,y | 0.022 | 0.119 | 0.648 | ||||||
≥60 | 0.778(0.642,0.944) | 0.011 | 0.603(0.332,1.094) | 0.096 | 1.316(1.045,1.656) | 0.019 | |||
< 60 | 0.827(0.657,1.040) | 0.104 | 0.885(0.440,1.779) | 0.731 | 1.45(1.044,2.012) | 0.026 | |||
Sex | 0.771 | 0.358 | 0.197 | ||||||
Male | 0.774(0.633,0.946) | 0.012 | 0.913(0.48,1.735) | 0.78 | 1.528(1.153,2.026) | 0.003 | |||
Female | 0.862(0.703,1.057) | 0.152 | 0.616(0.34,1.115) | 0.11 | 1.202(0.949,1.524) | 0.127 | |||
Smoke | 0.695 | 0.196 | 0.265 | ||||||
Yes | 0.658(0.490,0.885) | 0.006 | 1.131(0.489,2.615) | 0.773 | 1.580(1.096,2.277) | 0.014 | |||
No | 0.840(0.713,0.989) | 0.036 | 0.619(0.372,1.029) | 0.064 | 1.240(1.008,1.525) | 0.041 | |||
Alcohol consumption | 0.333 | 0.395 | 0.399 | ||||||
Yes | 0.645(0.428,0.972) | 0.036 | 1.166(0.344,3.952) | 0.805 | 1.489(0.849,2.612) | 0.165 | |||
No | 0.831(0.713,0.967) | 0.017 | 0.702(0.440,1.12) | 0.137 | 1.285(1.063,1.555) | 0.01 | |||
CAD | 0.293 | 0.114 | 0.639 | ||||||
Yes | 0.967(0.265,3.531) | 0.959 | 0.186(0,Inf) | 1 | 0.195(0,Inf) | 1 | |||
No | 0.802(0.695,0.926) | 0.003 | 0.777(0.504,1.199) | 0.255 | 1.32(1.102,1.581) | 0.003 | |||
Stroke | 0.005 | 0.219 | 0.126 | ||||||
Yes | 3.547(1.236,10.181) | 0.019 | 0.000(0.000,50.287) | 0.123 | 0(0,Inf) | 1 | |||
No | 0.775(0.671,0.895) | 0.001 | 0.763(0.494,1.179) | 0.223 | 1.288(1.076,1.542) | 0.006 | |||
BMI, kg/m2 | 0.411 | 0.099 | 0.417 | ||||||
≥24 | 0.827(0.691,0.990) | 0.039 | 0.764(0.448,1.302) | 0.322 | 1.349(1.083,1.681) | 0.008 | |||
< 24 | 0.993(0.914,1.079) | 0.869 | 0.597(0.273,1.306) | 0.197 | 1.314(0.952,1.815) | 0.097 | |||
Statin | 0.622 | 0.748 | 0.049 | ||||||
Yes | 0.996(0.990,1.002) | 0.207 | 1.000(0.969,1.031) | 0.982 | 1.027(1.009,1.045) | 0.003 | |||
No | 0.994(0.989,0.999) | 0.010 | 0.992(0.981,1.004) | 0.216 | 1.005(1.000,1.010) | 0.034 |