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Table 1 General characteristics of the study population according to IR positive and IR negative

From: Elevated triglyceride-to-HDL cholesterol ratio is an indicator for insulin resistance in middle-aged and elderly Taiwanese population: a cross-sectional study

Variables Insulin Resistance
Total IR positive IR negative  
(n = 398) (n = 123) (2) (n = 275) (< 2) p-value
Age (year) 64.43 ±8.45 64.59 ±7.86 64.36 ±8.71 0.80
SBP (mmHg) 129.57 ±16.72 133.97 ±16.49 127.60 ±16.47 < 0.001
DBP (mmHg) 76.94 ±11.36 78.91 ±10.66 76.06 ±11.57 0.02
BMI (kg/m2) 24.54 ±3.57 26.43 ±3.69 23.70 ±3.18 < 0.001
Waist circumference (cm) 84.99 ±9.62 90.51 ±9.86 82.53 ±8.43 < 0.001
ALT (U/L) 22.66 ±12.97 27.28 ±17.01 20.60 ±10.06 < 0.001
Creatinine (mg/dL) 0.77 ±0.42 0.78 ±0.33 0.77 ±0.45 0.88
eGFR (ml/min/1.73m2) 113.25 ±33.21 109.95 ±31.90 114.73 ±33.73 0.19
FPG (mg/dL) 95.54 ±22.32 110.06 ±31.81 89.05 ±11.59 < 0.001
HDL-C (mg/dL) 54.51 ±13.91 48.68 ±11.37 57.12 ±14.17 < 0.001
HOMA-IR index 1.86 ±1.39 3.39 ±1.58 1.18 ±0.44 < 0.001
LDL-C (mg/dL) 118.47 ±32.16 112.11 ±29.83 121.31 ±32.80 0.01
Total Cholesterol (mg/dL) 197.19 ±35.69 191.46 ±34.08 119.75 ±36.16 0.03
TG/HDL 2.52 ±1.83 3.48 ±2.32 2.09 ±1.37 < 0.001
Triglyceride (mg/dL) 121.20 ±62.93 153.46 ±76.04 106.77 ±49.88 < 0.001
Uric Acid (mg/dL) 5.74 ±1.41 6.10 ±1.36 5.58 ±1.41 0.001
WBC (1000/uL) 6.04 ±1.59 6.71 ±1.79 5.74 ±1.39 < 0.001
Men, n(%) 139 (34.9) 41 (33.3) 98 (35.6) 0.66
Current smoking, n(%) 42 (10.6) 12 (9.8) 30 (10.9) 0.73
Alcohol drinking 2 times/week, n(%) 75 (18.8) 17 (13.8) 58 (21.1) 0.09
Regular exercise, n(%) 326 (81.9) 92 (74.8) 234 (85.1) 0.01
Vegetarian, n(%) 22 (5.5) 5 (4.1) 17 (6.2) 0.39
ACR 30 mg/g, n(%) 74 (18.6) 31 (25.2) 43 (15.6) 0.02
HTN, n(%) 199 (50.0) 84 (68.3) 115 (41.8) < 0.001
DM, n(%) 77 (19.3) 48 (39.0) 29 (10.5) < 0.001
Hyperlipidemia, n(%) 259 (65.1) 93 (75.6) 166 (60.4) 0.003
Metabolic syndrome 141 (35.4) 89 (72.4) 52 (18.9) < 0.001
  1. Notes: Clinical characteristics are expressed as mean ± SD for continuous variables and n (%) for categorical variables. P-value were derived from independent two-sample t-test for continuous variables and chi-square test for categorical variables
  2. Abbreviations: SBP systolic blood pressure; DBP diastolic blood pressure; BMI body mass index; eGFR estimated glomerular filtration rate; FPG fasting plasma glucose; HDL-C high-density lipoprotein cholesterol; LDL-C low-density lipoprotein cholesterol; WBC white blood cell count; ACR albumin to creatinine ratio; HTN hypertension; DM diabetes mellitus