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Table 1 Mean values of FNDC5 gene expression fold change in pilot study after 3- and 12-h incubation

From: Upregulation of FNDC5 gene expression in C2C12 cells after single and combined treatments of resveratrol and ATRA

Groups

3 h incubation

12 h incubation

Valuea

P valueb

Valuea

P valueb

ATRA (0.1 μM)

0.50 ± 0.52

>  0.9

4.79 ± 4.86

0.9

ATRA (1.0 μM)

0.92 ± 0.45

>  0.9

16.09 ± 6.01

0.9

ATRA (10 μM)

3.90 ± 2.07

0.6

15.24 ± 21.39

0.4

Res (0.1 μM)

2.72 ± 2.16

0.9

15.68 ± 4.41

0.4

Res (1.0 μM)

4.15 ± 2.27

0.5

8.77 ± 5.60

0.4

Res (25 μM)

1.33 ± 0.82

>  0.9

11.90 ± 6.30

0.9

Res (50 μM)

4.15 ± 4.35

0.5

4.80 ± 3.87

0.7

Vehicle

1.05 ± 0.45

–

1.03 ± 0.32

–

  1. aData were represented as mean ± SD (n = 2)
  2. b Comparing each group with the vehicle group (The mean difference is significant at the 0.05 level)