Study, year | Arms | No | EF % | Age Year | BMI | Male % | DM % | HTN % | Smoking % | TC mmol/L | Triglyceride mmol/L |
---|---|---|---|---|---|---|---|---|---|---|---|
Horwich et al. 2004 | S C | 200 250 | ≤40% ≤40% | 57 ± 11 48 ± 13 | 28.2 ± 6.2 26.9 ± 6.2 | 82 70 | 33 16 | 64 43 | 80 66 | 4.32 ± 1.25 4.2 ± 1.5 | 1.87 ± 1.3 1.98 ± 2.17 |
Sola et al. 2005 | S C | 225 191 | ≤35% ≤35% | 55.4 ± 6.4 53.8.4 ± 5.7 | 24.3 ± 3.8 23.5 ± 4.3 | 62 63 | 24 27 | 41 36 | 34 30 | NR NR | 2.8 ± 0.5 2.9 ± 0.4 |
Fukuta et al. 2005 | S C | 69 68 | ≥50% ≥50% | 65 ± 2 65 ± 16 | NR NR | 51 45 | 34 12 | 87 72 | NR NR | 6.07 ± 2.22 4.67 ± 1 | 2.31 ± 2.21 1.64 ± 0.90 |
Hong et al. 2005 | S C | 106 96 | ≤40% ≤40% | 61.8 ± 10.3 60.9 ± 10.4 | NR NR | 72 75 | 32 28 | 41 44 | 57 52 | NR NR | NR NR |
Go et al. 2006 | S C | 12,648 11,950 | ≤40% ≤40% | 69.6 ± 10.3 72.9 ± 11.4 | NR NR | 62 60 | 55.7 41.3 | 89 83 | NR NR | 5.37 ± 1.14 5.68 ± 1.22 | NR NR |
Kjekshus et al. 2007 | S C | 2514 2497 | ≤40% ≤40% | 73 ± 7.1 73 ± 7.0 | 27 ± 4.5 27 ± 4.6 | 76 76 | 30 29 | 63 63 | 9 8 | 5.36 ± 1.11 5.35 ± 1.06 | 2.01 ± 1.33 1.99 ± 1.23 |
Huan et al. 2007 | S C | 377 102 | ≤40% ≤40% | 74 ± 4 74 ± 3 | 26.5 28.1 | 66 77 | NR NR | NR NR | 75 72 | 5.1 ± 0.25 5.5 ± 0.3 | NR NR |
Coleman et al. 2008 | S C | 642 562 | ≤30% ≤30% | 67.5 ± 13 64.5 ± 10.8 | NR NR | 80.7 76.2 | 31.5 30.2 | 43.8 34.9 | NR NR | NR NR | NR NR |
Roik et al. 2008 | S C | 103 43 | ≥45% ≥45% | 69 ± 11 66 ± 16 | 28.6 ± 4.8 27.2 ± 4.9 | 50.5 58 | 25 12 | 76 58 | 43 34 | 4.57 ± 1.37 4.57 ± 1.03 | 1.64 ± 1.08 1.62 ± 1.05 |
Tavazzi et al. 2008 the GISSI-HF trial | S C | 2285 2289 | 33.4 33.4 | 68 ± 1 68 ± 1 | 27·1 ± 4.6 27.71 ± 4.4 | 78.6 76.8 | 25 27.4 | 53.5 55.1 | 14.1 14 | NR NR | NR NR |
Gomez-Soto et al. 2010 | S C | 1343 1230 | ≥47% ≥47% | 71.5 ± 6.9 69.8 ± 7.8 | NR NR | 51.6 43.9 | 36.8 47.7 | 45.6 48.5 | 33 31 | NR NR | NR NR |
Kaneko et al. 2013 | S C | 459 665 | ≥50% ≥50% | 65.6 ± 11.7* | 24.3 ± 3.6* | 76.2* | 32.4* | 64.5* | 24.2* | NR NR | NR NR |
Yap et al. 2015 | S C | 457 293 | ≥50% ≥50% | 73.1 ± 10.6* | 26.5* | 35.3* | 47.1* | 80.3* | NR NR | NR NR | NR NR |
Nochioka et al. 2015 | S C | 1163 1961 | ≥50% ≥50% | 69.0 ± 11.0 69.7 ± 12.9 | 67.5 64 | 45 40.8 | 33.8 20.9 | 85 76.7 | 45 40.8 | NR NR | 1.51 ± 0.82 1.4 ± 0.81 |
Alehagen U et al. 2015 | S C | 3427 5713 | ≥50% ≥50% | 78 ± 12 75 ± 9 | 29 ± 6 27 ± 6 | 54 42 | 31 28 | 62 64 | NR NR | NR NR | NR NR |
Alehagen et al. 2015 | S C | 10,345 11,519 | < 40% < 40% | 72 10 72 ± 14 | 27 ± 5 26 ± 5 | 75 68 | 33 18 | 48 39 | 41 49 | NR NR | NR NR |
Tsujimoto et al. 2018 | S C | 1765 1613 | ≥50% ≥50% | 69 ± 9.6 68.1 ± 9.6 | NR NR | 55 42 | 42.9 20.8 | 93.1 89.8 | 10.5 10.6 | NR NR | NR NR |