LncRNA SNHG8 is identified as a key regulator of acute myocardial infarction by RNA-seq analysis

Table 3 Comparison of demographic and lifestyle characteristics and serum lipid levels between the normal and AMI groups

Parameter	Control	AMI	test-statistic	P
Number	115	115
Male/female	35/80	36/79	0.020	0.886
Age (years)^a	54.3 ± 9.4	55.1 ± 10.1	0.854	0.491
Height (cm)	154.2 ± 6.9	155.5 ± 7.1	1.592	0.212
Weight (kg)	52.9 ± 7.6	60.5 ± 10.8	20.439	1.67E-005
Body mass index (kg/m²)	22.76 ± 2.94	23.69 ± 3.28	−2.317	0.021
Waist circumference (cm)	73.4 ± 6.6	87.5 ± 9.9	23.122	3.34E-005
Smoking status [n (%)]	29(25.1)	43(37.8)	7.690	0.005
Alcohol consumption [n (%)]	27(23.4)	25(22.3)	0.309	0.578
Systolic blood pressure (mmHg)	127.2 ± 18.2	132.5 ± 21.2	0.693	0.231
Diastolic blood pressure (mmHg)	80.5 ± 10.3	81.5 ± 13.2	0.707	0.281
Pulse pressure (mmHg)	47.6 ± 13.1	49.3 ± 13.6	1.582	0.213
Glucose (mmol/L)	5.92 ± 1.81	7.61 ± 2.71	15.867	2.71E-005
Total cholesterol (mmol/L)	4.91 ± 1.23	5.64 ± 1.26	9.122	0.006
Triglyceride (mmol/L)^b	1.47(0.50)	1.52(1.21)	2.116	0.154
HDL-C (mmol/L)	1.43 ± 0.41	1.16 ± 0.14	8.677	0.014
LDL-C (mmol/L)	2.93 ± 0.82	3.89 ± 0.74	10.491	0.002
ApoA1 (g/L)	1.21 ± 0.25	1.27 ± 0.27	0.381	0.518
ApoB (g/L)	0.86 ± 0.17	0.91 ± 0.22	1.563	0.192
ApoA1/ApoB	1.7 ± 0.5	1.7 ± 0.6	0.095	0.758
Heart rate (beats/minutes)	73.5 ± 10.6	72.2 ± 13.4	0.413	0.44
Creatinine, (μmol/L)	72.61 ± 12.35	75.87 ± 13.88	8.694	0.010
Uric acid, (μmol/L)	282.10 ± 74.64	282.13 ± 72.61	0.273	0.744
Troponin T, (μg/L)	0.01 ± 0.02	1.71 ± 2.81	12.437	1.58E-005
CK, (U/L)	86.30 ± 47.68	1007.07 ± 1502.9	16.812	3.89E-005
CKMB, (U/L)	13.73 ± 4.53	115.85 ± 169.70	17.889	4.76E-005

HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Apo Apolipoprotein, CK creatine kinase, CKMB creatine kinase-myocardial band ^aMean ± SD determined by t-test. ^bBecause it was not normally distributed, the value of triglyceride content was presented as median (interquartile range), and the difference between the two groups was determined by the Wilcoxon-Mann-Whitney test

ISSN: 1476-511X