Bee pollen and propolis improve neuroinflammation and dysbiosis induced by propionic acid, a short chain fatty acid in a rodent model of autism

Table 2 Multiple regression analyses using a stepwise method with IL-12 (P70) (pg/ml) and TNFα (pg/ml) as dependent variables

Dependent variables	Predictor variables	Coefficients	P values	Adjusted R²	95% CIs
Dependent variables	Predictor variables	Coefficients	P values	Adjusted R²	Lower	Upper
IL-12 (P70) (pg/ml)	TNFα	3.454	0.000	0.526	2.227	4.681
	TNFα	3.873	0.000	0.577	2.641	5.106
	VEGF	−1.755	0.047	0.577	−3.480	−0.029
	TNFα	3.874	0.000	0.631	2.720	5.027
	VEGF	−2.143	0.013		−3.798	−0.489
	IL-1A	0.056	0.035		0.004	0.108
TNFα (pg/ml)	IL-12 (P70) (pg/ml)	0.157	0.000	0.526	0.101	0.213
	IL-12 (P70) (pg/ml)	0.157	0.000	0.624	0.107	0.206
	VEGF (pg/ml)	0.459	0.008	0.624	0.132	0.786

IL-12, interleukin-12; TNFα, tumor necrosis factor α; CIs, confidence intervals; VEGF, vascular endothelial growth factor

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