|
Parameters
|
Groups
|
AUC
|
Cut-off value
|
Sensitivity %
|
Specificity %
|
P value
|
95% CI
|
|---|
|
IFN-γ (pg/ml)
|
PPA
|
0.500
|
25.380
|
50.0%
|
66.7%
|
1.000
|
0.153–0.847
|
|
Bee pollen
|
0.889
|
8.445
|
83.3%
|
100.0%
|
0.025
|
0.673–1.105
|
|
Propolis
|
0.667
|
17.380
|
83.3%
|
66.7%
|
0.337
|
0.331–1.002
|
|
IL-1A (pg/ml)
|
PPA
|
0.694
|
172.545
|
66.7%
|
66.7%
|
0.262
|
0.385–1.004
|
|
Bee pollen
|
0.861
|
129.458
|
66.7%
|
100.0%
|
0.037
|
0.645–1.077
|
|
Propolis
|
0.569
|
152.360
|
83.3%
|
50.0%
|
0.689
|
0.210–0.928
|
|
IL-6 (pg/ml)
|
PPA
|
0.833
|
23.195
|
83.3%
|
83.3%
|
0.055
|
0.570–1.096
|
|
Bee pollen
|
0.667
|
16.880
|
66.7%
|
83.3%
|
0.337
|
0.317–1.017
|
|
Propolis
|
0.583
|
18.145
|
66.7%
|
66.7%
|
0.631
|
0.241–0.926
|
|
IL-10 (PG/ML)
|
PPA
|
0.917
|
122.270
|
100.0%
|
83.3%
|
0.016
|
0.742–1.091
|
|
Bee pollen
|
0.889
|
119.215
|
100.0%
|
83.3%
|
0.025
|
0.673–1.105
|
|
Propolis
|
0.597
|
122.055
|
66.7%
|
83.3%
|
0.575
|
0.239–0.956
|
|
IL-12 (P70) (pg/ml)
|
PPA
|
0.833
|
72.835
|
66.7%
|
100.0%
|
0.055
|
0.593–1.073
|
|
Bee pollen
|
0.861
|
72.130
|
83.3%
|
100.0%
|
0.037
|
0.604–1.119
|
|
Propolis
|
0.903
|
72.130
|
83.3%
|
100.0%
|
0.020
|
0.708–1.098
|
|
VEGF (pg/ml)
|
PPA
|
0.597
|
4.500
|
66.7%
|
66.7%
|
0.575
|
0.253–0.941
|
|
Bee pollen
|
0.889
|
4.240
|
83.3%
|
83.3%
|
0.025
|
0.697–1.081
|
|
Propolis
|
0.944
|
3.645
|
83.3%
|
100.0%
|
0.010
|
0.814–1.075
|
|
TNFα (pg/ml)
|
PPA
|
0.944
|
15.095
|
83.3%
|
100.0%
|
0.010
|
0.814–1.075
|
|
Bee pollen
|
0.833
|
14.845
|
83.3%
|
100.0%
|
0.055
|
0.535–1.132
|
|
Propolis
|
1.000
|
14.680
|
100.0%
|
100.0%
|
0.004
|
1.000–1.000
|
- ROC, receiver operating characteristics curve; AUC, area under the curve; IFN-γ, interferon γ
