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Table 2 Effects of ATGL deficiency in mice on glucose metabolism across various tissues compared to control littermates

From: The role of adipose triglyceride lipase in lipid and glucose homeostasis: lessons from transgenic mice

Tissue of Interest
Tissue-knockout Liver WAT BAT Heart Skeletal muscle
Globala Increased gluconeogenesis
Decreased fasting glycogen
Increased uptake
Increased glucose oxidation
Increased glucose oxidation Decreased glycolysis Increased glucose oxidation
Liverb No change No change No change No change No change
Adiposec Increased gluconeogenesis
Decreased glycogen levels
Increased glucose uptake Increased glucose oxidation Increased glucose oxidation Increased glucose oxidation
BATd Unknown Unknown No change Unknown No change
Hearte Unknown Unknown Unknown Decreased glycolysis No change
Skeletal musclef No change No change No change No change No change
Pancreasg Unknown Unknown Unknown Unknown Unknown
  1. a key reference: [15], b key references: [55, 56], c key references: [28, 33, 34], d key references: [31, 32], e key references: [17,18,19,20], f key references: [36, 39, 47], g key references: [25, 61, 62]