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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet

Fig. 3

Pioglitazone promotes LD-induced decrease of HMGCR or SREBP-2 and inhibited decrease in CYP7A1 in liver. a Western blot analysis of HMGCR, SREBP-2 and CYP7A1 protein; b Quantification of HMGCR expressed as the ratio (as a percentage) of control; c Quantification of SREBP-2 expressed as the ratio (as a percentage) of control; d Quantification of CYP7A1 expressed as the ratio (as a percentage) of control. Values shown are means ± SD, n = 4. *p < 0.05 and **p < 0.01 versus LD group

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