Fig. 3From: Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic dietPioglitazone promotes LD-induced decrease of HMGCR or SREBP-2 and inhibited decrease in CYP7A1 in liver. a Western blot analysis of HMGCR, SREBP-2 and CYP7A1 protein; b Quantification of HMGCR expressed as the ratio (as a percentage) of control; c Quantification of SREBP-2 expressed as the ratio (as a percentage) of control; d Quantification of CYP7A1 expressed as the ratio (as a percentage) of control. Values shown are means ± SD, n = 4. *p < 0.05 and **p < 0.01 versus LD groupBack to article page