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Table 1 Pioglitazone treatment alters biliary composition and CSI in the guinea pigs fed with LD

From: Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet

VariablesCTRLLDPIO-LPIO-HEZE
CH (mmol/L)2.93 ± 1.14**8.39 ± 1.647.05 ± 1.685.65 ± 1.33**5.07 ± 1.30**
BA (mmol/L)56.09 ± 9.86**77.02 ± 9.8680.59 ± 9.7792.26 ± 8.46**85.47 ± 8.91
PL (mmol/L)22.89 ± 5.1525.65 ± 4.8926.33 ± 4.6827.47 ± 5.2726.22 ± 4.56
CSI0.57 ± 0.17**1.13 ± 0.150.85 ± 0.13*0.70 ± 0.13**0.67 ± 0.10**
  1. Values are expressed as means ± SD (n = 8). P < 0.05 and P < 0.01 versus LD group