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Table 1 Pioglitazone treatment alters biliary composition and CSI in the guinea pigs fed with LD

From: Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet

Variables

CTRL

LD

PIO-L

PIO-H

EZE

CH (mmol/L)

2.93 ± 1.14**

8.39 ± 1.64

7.05 ± 1.68

5.65 ± 1.33**

5.07 ± 1.30**

BA (mmol/L)

56.09 ± 9.86**

77.02 ± 9.86

80.59 ± 9.77

92.26 ± 8.46**

85.47 ± 8.91

PL (mmol/L)

22.89 ± 5.15

25.65 ± 4.89

26.33 ± 4.68

27.47 ± 5.27

26.22 ± 4.56

CSI

0.57 ± 0.17**

1.13 ± 0.15

0.85 ± 0.13*

0.70 ± 0.13**

0.67 ± 0.10**

  1. Values are expressed as means ± SD (n = 8). ∗P < 0.05 and ∗∗P < 0.01 versus LD group
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Lipids in Health and Disease

ISSN: 1476-511X