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Table 2 Effects of pioglitazone on metabolic parameters

From: Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet

VariablesCTRLLDPIO-LPIO-HEZE
Body weight (g)479.39 ± 50.97511.83 ± 70.00490.13 ± 40.78435.46 ± 69.62*492.46 ± 63.29
Blood glucose (mmol/L)3.35 ± 0.523.90 ± 0.633.39 ± 0.682.99 ± 0.39**3.43 ± 0.51
Insulin (mmol/L)2.45 ± 0.533.00 ± 0.542.58 ± 0.592.40 ± 0.53*2.51 ± 0.29
CH (mmol/L)3.60 ± 0.74**6.28 ± 0.915.85 ± 0.775.04 ± 1.07*4.36 ± 0.81**
TG (mmol/L)0.37 ± 0.07**0.63 ± 0.100.50 ± 0.10*0.44 ± 0.10**0.47 ± 0.09**
LDL-C(mmol/L)1.39 ± 0.19**2.02 ± 0.301.84 ± 0.271.72 ± 0.27*1.64 ± 0.18*
HDL-C (mmol/L)1.03 ± 0.20**0.69 ± 0.190.77 ± 0.140.91 ± 0.10*0.94 ± 0.18*
  1. Values are expressed as means ± SD (n = 8). P < 0.05 and P < 0.01 versus LD