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Table 2 Effects of pioglitazone on metabolic parameters

From: Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet

Variables

CTRL

LD

PIO-L

PIO-H

EZE

Body weight (g)

479.39 ± 50.97

511.83 ± 70.00

490.13 ± 40.78

435.46 ± 69.62*

492.46 ± 63.29

Blood glucose (mmol/L)

3.35 ± 0.52

3.90 ± 0.63

3.39 ± 0.68

2.99 ± 0.39**

3.43 ± 0.51

Insulin (mmol/L)

2.45 ± 0.53

3.00 ± 0.54

2.58 ± 0.59

2.40 ± 0.53*

2.51 ± 0.29

CH (mmol/L)

3.60 ± 0.74**

6.28 ± 0.91

5.85 ± 0.77

5.04 ± 1.07*

4.36 ± 0.81**

TG (mmol/L)

0.37 ± 0.07**

0.63 ± 0.10

0.50 ± 0.10*

0.44 ± 0.10**

0.47 ± 0.09**

LDL-C(mmol/L)

1.39 ± 0.19**

2.02 ± 0.30

1.84 ± 0.27

1.72 ± 0.27*

1.64 ± 0.18*

HDL-C (mmol/L)

1.03 ± 0.20**

0.69 ± 0.19

0.77 ± 0.14

0.91 ± 0.10*

0.94 ± 0.18*

  1. Values are expressed as means ± SD (n = 8). P < 0.05 and P < 0.01 versus LD