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Table 1 Summary of analysis of LXA4 and BDNF levels in the supernatant of RIN5F treated with Alloxan (Pre-treatment)/STZ (Simultaneous treatment) and sub-optimal doses of AA (10 μg/ml) and BDNF (50 ng/ml)

From: PUFAs, BDNF and lipoxin A4 inhibit chemical-induced cytotoxicity of RIN5F cells in vitro and streptozotocin-induced type 2 diabetes mellitus in vivo

SUMMARY OF LIPOXIN A4 LEVELS AND BDNF LEVELS IN CHEMICAL(AL/STZ/DB/BP) INDUCED CYTOTOXICITY IN RIN5F CELLS INVITRO (supernatants)
ELISAGROUPAL studiez (6 mM)STZ studies (20 mM)DB studies (100 ng/ml)BP studies (1.5 mM)
LXA4 levels (ng/ml)CONTROL0.83 ± 0.20.91 ± 0.31.22 ± 0.30.75 ± 0.2
CYTOTOXIN0.5 ± 0.12*0.37 ± 0.2*0.67 ± 0.6*0.41 ± 0.1*
BDNF levels (pg/ml)CONTROL36.9 ± 0.925.3 ± 0.837.3 ± 0.4042.2 ± 0.3
CYTOTOXIN14.4 ± 0.2*18.2 ± 0.3*23.4 ± 0.36*28.3 ± 0.9*
  1. * P < 0.01