Table 1 Summary of analysis of LXA4 and BDNF levels in the supernatant of RIN5F treated with Alloxan (Pre-treatment)/STZ (Simultaneous treatment) and sub-optimal doses of AA (10 μg/ml) and BDNF (50 ng/ml)

ELISA

GROUP

AL studiez (6 mM)

STZ studies (20 mM)

DB studies (100 ng/ml)

BP studies (1.5 mM)

LXA4 levels (ng/ml)

CONTROL

0.83 ± 0.2

0.91 ± 0.3

1.22 ± 0.3

0.75 ± 0.2

CYTOTOXIN

0.5 ± 0.12*

0.37 ± 0.2*

0.67 ± 0.6*

0.41 ± 0.1*

BDNF levels (pg/ml)

CONTROL

36.9 ± 0.9

25.3 ± 0.8

37.3 ± 0.40

42.2 ± 0.3

CYTOTOXIN

14.4 ± 0.2*

18.2 ± 0.3*

23.4 ± 0.36*

28.3 ± 0.9*