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Table 3 Summary of Lipid peroxides and nitric oxide analysis in RIN5F cells treated with Alloxan (Pre-treatment) /STZ(Simultaneous) and suboptimal doses of AA (10 μg/ml) + BDNF (50 ng/ml)

From: PUFAs, BDNF and lipoxin A4 inhibit chemical-induced cytotoxicity of RIN5F cells in vitro and streptozotocin-induced type 2 diabetes mellitus in vivo

SUMMARY OF THE ANALYSIS OF LIPID PEROXIDES AND NITRIC OXIDE LEVELS IN RIN5F CELLS TREATED WITH AL/STZ
CHEMICALGROUPLIPID PEROXIDES (μM TMOP)NITRIC OXIDE (μM Nitrite)
Supernatant LysatesSupernatant Lysates
ALLOXANCONTROL0.47 ± 0.041.2 ± 0.040.58 ± 0.031.2 ± 0.03
AL(6 mM)0.8 ± 0.04*1.6 ± 0.09*0.87 ± 0.051.4 ± 0.05*
AA(10 μg/ml)0.45 ± 0.061.1 ± 0.020.54 ± 0.061.15 ± 0.03
BDNF(50 ng/ml)0.44 ± 0.031.3 ± 0.050.43 ± 0.031.18 ± 0.07
AA + BDNF0.37 ± 0.031.3 ± 0.10.49 ± 0.041.16 ± 0.05
AL + AA(10 μg/ml)1.2 ± 0.03#1.3 ± 0.05#1.42 ± 0.03 #1.16 ± 0.05 #
AL + BDNF0.9 ± 0.03§0.9 ± 0.05§0.94 ± 0.03§1.25 ± 0.02§
AL + AA + BDNF0.74 ± 0.061.4 ± 0.050.89 ± 0.071.12 ± 0.05
STREPTOZOTOCINCONTROL0.68 ± 0.051.3 ± 0.040.64 ± 0.041.08 ± 0.05
STZ(20 mM)0.89 ± 0.031.6 ± 0.090.83 ± 0.041.52 ± 0.06
AA(10 μg/ml)0.55 ± 0.031.2 ± 0.020.61 ± 0.051.11 ± 0.02
BDNF(50 ng/ml)0.54 ± 0.011.2 ± 0.030.57 ± 0.021.09 ± 0.02
AA + BDNF0.51 ± 0.031.2 ± 0.030.58 ± 0.011.11 ± 0.05
STZ + AA(10 μg/ml)0.72 ± 0.06#0.9 ± 0.09#0.79 ± 0.07#1.09 ± 0.04#
STZ + BDNF0.66 ± 0.08§0.8 ± 0.09§0.69 ± 0.4§0.9 ± 0.08§
STZ + AA + BDNF0.59 ± 0.031.3 ± 0.030.65 ± 0.01.15 ± 0.05
  1. Lipid peroxides formed are expressed as μmoles of TMOP formed; Nitric oxide formed is expressed as μ moles of nitrite formed. *P < 0.001 Vs Untreated control and § P ≤ 0.05, # P ≤ 0.02, * P < 0.01, ** P < 0.001 Vs AL/STZ -treated group