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Table 5 Summary of Lipid peroxides and nitric oxide analysis in RIN5F treated with BP(Pre-treatment) /DB(Simultaneous) and suboptimal doses of AA (10 μg/ml) + BDNF(50 ng/ml)

From: PUFAs, BDNF and lipoxin A4 inhibit chemical-induced cytotoxicity of RIN5F cells in vitro and streptozotocin-induced type 2 diabetes mellitus in vivo

SUMMARY OF THE ANALYSIS OF LIPID PEROXIDES AND NITRIC OXIDE LEVELS IN RIN5F CELLS TREATED WITH DB/BP
CHEMICALGROUPLIPID PEROXIDES (μM TMOP)NITRIC OXIDE (μM Nitrite)
Supernatant LysatesSupernatant Lysates
DOXORUBICINCONTROL0.43 ± 0.031.1 ± 0.030.71 ± 0.020.9 ± 0.03
DB(100 ng/ml)0.75 ± 0.021.8 ± 0.040.91 ± 0.041.2 ± 0.03
AA(10 μg/ml)0.23 ± 0.021.1 ± 0.030.49 ± 0.02§1.2 ± 0.02§
BDNF(50 ng/ml)0.37 ± 0.021.3 ± 0.040.41 ± 0.011.2 ± 0.06
AA + BDNF0.48 ± 0.011.1 ± 0.090.39 ± 0.011.2 ± 0.04
DB + AA(10 μg/ml)0.55 ± 0.04#1.2 ± 0.051.02 ± 0.02#1.1 ± 0.04
DB + BDNF0.61 ± 0.03§0.87 ± 0.02§0.91 ± 0.01§0.88 ± 0.08§
DB + AA + BDNF0.59 ± 0.031.2 ± 0.060.79 ± 0.031.1 ± 0.05
BENZOPYRENECONTROL0.58 ± 0.020.8 ± 0.020.74 ± 0.020.98 ± 0.05
BP(1.5 mM)0.99 ± 0.011.6 ± 0.030.99 ± 0.031.4 ± 0.06
AA(10 μg/ml)0.61 ± 0.041.1 ± 0.030.69 ± 0.011.11 ± 0.02
BDNF(50 ng/ml)0.59 ± 0.020.89 ± 0.010.61 ± 0.031.07 ± 0.03
AA + BDNF0.61 ± 0.011.2 ± 0.020.72 ± 0.011.09 ± 0.04
BP + AA(10 μg/ml)0.69 ± 0.05#0.89 ± 0.04#0.69 ± 0.07#1.05 ± 0.02#
BP + BDNF0.72 ± 0.03§0.7 ± 0.05§0.71 ± 0.4§1.1 ± 0.07§
BP + AA + BDNF0.64 ± 0.061.1 ± 0.020.79 ± 0.011.23 ± 0.03
  1. Lipid peroxides formed are expressed as μmoles of TMOP formed; Nitric oxide formed is expressed as μ moles of nitrite formed. *P < 0.01 Vs Untreated control and § P ≤ 0.05, # P ≤ 0.02, * P < 0.01, ** P < 0.001 Vs DB/BP -treated group