Table 3 Subgroup analyses on major cardiovascular events
Subgroup | No. of studies | Pooled risk ratios | 95% confidence intervals | Heterogeneity between studies |
|---|---|---|---|---|
Sample sizes | ||||
< 500 | 6 | 1.07 | 0.76–1.54 | p < 0.001; I2 = 83.0% |
≥ 500 | 2 | 1.16 | 0.82–1.65 | p = 0.130; I2 = 56.5% |
Type of patients | ||||
All CAD | 2 | 0.67 | 0.28–1.59 | p = 0.006; I2 = 86.8% |
ACS | 3 | 1.23 | 1.03–1.47 | p = 0.180; I2 = 41.7% |
Follow-up duration | ||||
< 3 years | 4 | 0.84 | 0.36–1.97 | p < 0.001; I2 = 86.5% |
≥ 3 years | 4 | 1.31 | 1.02–1.68 | p = 0.038; I2 = 64.5% |
Adjustment of LVEF | ||||
Yes | 5 | 1.24 | 0.72–2.12 | p < 0.001; I2 = 84.1% |
No | 3 | 1.11 | 0.86–1.44 | p = 0.034; I2 = 70.3% |
Newcastle–Ottawa Scale | ||||
≥ 7 stars | 6 | 1.01 | 0.71–1.44 | p < 0.001; I2 = 82.2% |
< 7 stars | 2 | 2.02 | 0.53–7.70 | p = 0.068; I2 = 70.1% |