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Table 3 Subgroup analyses on major cardiovascular events

From: Prognostic value of adiponectin level in patients with coronary artery disease: a systematic review and meta-analysis

SubgroupNo. of studiesPooled risk ratios95% confidence intervalsHeterogeneity between studies
Sample sizes
 < 50061.070.76–1.54p < 0.001; I2 = 83.0%
 ≥ 50021.160.82–1.65p = 0.130; I2 = 56.5%
Type of patients
 All CAD20.670.28–1.59p = 0.006; I2 = 86.8%
 ACS31.231.03–1.47p = 0.180; I2 = 41.7%
Follow-up duration
 < 3 years40.840.36–1.97p < 0.001; I2 = 86.5%
 ≥ 3 years41.311.02–1.68p = 0.038; I2 = 64.5%
Adjustment of LVEF
 Yes51.240.72–2.12p < 0.001; I2 = 84.1%
 No31.110.86–1.44p = 0.034; I2 = 70.3%
Newcastle–Ottawa Scale
 ≥ 7 stars61.010.71–1.44p < 0.001; I2 = 82.2%
 < 7 stars22.020.53–7.70p = 0.068; I2 = 70.1%
  1. Abbreviations: ACS Acute coronary syndrome, CAD Coronary artery disease, LVEF Left ventricular ejection fraction