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Table 1 Characteristics of included studies

From: Effect of atorvastatin treatment on circulating adiponectin: a meta-analysis of randomized controlled trials

Author (year)

Design

Population

Number of subjects

Mean age

Male

Mean BMI

Dose

Follow-up durations

Adiponectin measurement

    

years

%

Kg/m2

mg/d

weeks

 

Shetty 2004

R, DB, PC

DM patients or subjects at risk for T2DM

77

51.1

55.8

29.2

20

12

RIA

Koh 2005

R, DB, PC, CO

Combined HL patients

56

56.0

41.1

25.5

10

8

ELISA

Chan 2008

R

Post-PCI CAD patients

60

65.0

71.7

25.5

10

24

RIA

von Eynatten 2009

R, SB, PC

T2DM patients

75

60.9

69.3

28.2

40

8

ELISA

van Hoek 2009–10 mga

R, DB, PC

T2DM patients

109

59.3

55.4

30.7

10

30

ELISA

van Hoek 2009–80 mga

R, DB, PC

T2DM patients

108

59.6

50.7

30.9

80

30

ELISA

Carnevale 2010

R, SB

HC patients

36

55.2

47.2

25.2

10

4

ELISA

Koh 2010–10 mgb

R, SB, PC

HC patients

53

55.6

51.2

24.8

10

8

ELISA

Koh 2010–20 mgb

R, SB, PC

HC patients

55

57.2

50.0

24.9

20

8

ELISA

Koh 2010–40 mgb

R, SB, PC

HC patients

54

58.0

51.7

25.0

40

8

ELISA

Koh 2010–80 mgb

R, SB, PC

HC patients

51

56.4

51.2

24.9

80

8

ELISA

Koh 2011

R, SB, PC, CO

HTN patients

42

53.0

52.4

25.5

20

8

RIA

El-Barbary 2011

R, OL

RA patients

30

54.2

16.7

25.7

40

24

ELISA

Buldak 2012

R, SB

HL patients with IFG

37

50.9

54.1

28.1

10

12

ELISA

  1. Abbreviations: BMI body mass index, R random, DB double-blinded, PC placebo controlled, CO crossover, SB single-blinded, OL open label, ELISA enzyme-linked immunosorbent assay, RIA radioimmunoassay, HC hypercholesterolemic, HL hyperlipidemic, HTN hypertension, T2DM type 2 diabetes mellitus, DM diabetes mellitus, CAD coronary artery disease, RA rheumatic arthritis, IFG impaired fasting glucose
  2. athe study by van Hoek et al. (2009) included two atorvastatin treatment arms with dosages of 10 and 80 mg/d respectively, and both the comparisons were included separately
  3. bthe study by Koh et al. (2010) included four atorvastatin treatment arms with dosages of 10, 20, 40, 80 mg/d respectively, and these comparisons were included separately