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Table 1 Characteristics and sterol profiles of studied subjects

From: Age-related changes of cholestanol and lathosterol plasma concentrations: an explorative study

ParametersNewborns(n = 24)Children(n = 33)Adults (n = 73)Multiple comparisons (p)
Overall significanceNewborns vs ChildrenNewborns vs AdultsChildren vs Adults
Gender (n° males and %)18 (75.0%)18 (54.5%)51 (69.9%)nsncncnc
Age (years) a0.25 (0.08–0.54)4.00 (2.75–6.96)34 (26.5–41.0)<  0.0001ncncnc
Cholesterol (mmol/L)3.24 (1.06)3.81 (0.90)4.35 (0.78)<  0.00010.047<  0.00010.011
Cholestanol (μmol/L) a8.36 (5.18–10.42)7.20 (5.90–8.67)5.29 (4.21–8.21)0.024nsnsns
Lathosterol (μmol/L)5.15 (2.97)4.83 (1.78)6.78 (2.81)0.0006ns0.0280.002
Cholestanol/Cholesterol (μmol/mmol) a2.46 (1.76–3.54)1.98 (1.49–2.26)1.34 (1.06–1.90)< 0.00010.0110.00010.002
Lathosterol/Cholesterol (μmol/mmol)1.72 (1.05)1.29 (0.40)1.57 (0.62)0.050nsnsns
Cholestanol/Lathosterol (μmol/μmol) a1.88 (1.20–2.40)1.66 (1.02–2.18)0.84 (0.59–1.53)0.001ns0.0010.001
  1. aData of non-parametric distributions are reported as median and interquartile range and the comparisons are performed by Kruskal-Wallis test
  2. ns not significant difference
  3. nc not calculated