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Table 4 Associations between the GUCY1A3 rs1842896 and rs7692387 with LAA stroke

From: Associations between GUCY1A3 genetic polymorphisms and large artery atherosclerotic stroke risk in Chinese Han population: a case-control study

Model

Crude OR (95% CI)

P-value

Adjusted OR (95% CI)

Adjusted P-value

rs1842896

Dominant (TT + GT vs. GG)

0.87 (0.49–1.55)

0.643

0.79 (0.34–1.83)

0.586

Recessive (TT vs. GT + GG)

1.48 (1.07–2.04)

0.018*

1.96 (1.22–3.17)

0.006*

Additive (TT vs. GG)

1.08 (0.59–1.95)

0.813

1.22 (0.51–2.93)

0.656

rs7692387

Dominant (GG + GA vs. AA)

0.91 (0.39–2.09)

0.819

1.48 (0.51–4.33)

0.472

Recessive (GG vs. GA + AA)

0.93 (0.67–1.30)

0.688

0.71 (0.43–1.17)

0.177

Additive (GG vs. AA)

0.89 (0.38–2.06)

0.782

1.28 (0.43–3.75)

0.657

  1. Adjusted for age, gender, cigarette smoking, total cholesterol, low-density lipoprotein cholesterol, HbA1c, hypertension history, diabetes mellitus history, and coronary artery disease history
  2. The entries in boldface are statistically significant
  3. *P < 0.05