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Table 3 Mean (±SD) values of calculated LDL-C by eight formulae for various HDL-C ranges and their correlation with directly measured LDL-C

From: Evaluation of eight formulas for LDL-C estimation in Iranian subjects with different metabolic health statuses

Method

Mean ± SD (mmol/L)

Mean Difference (mmol/L)

Correlation (r)

p-value obtained by paired t-test

HDL-C < 1.03 mmol/L (n = 382)

 Direct LDL-C

2.22 ± 0.47

   

 Friedewald LDL-C

2.16 ± 0.67

−0.05

0.902

0.007

 Chen LDL-C

2.38 ± 0.58

0.16

0.911

0.0001

 de Cordova LDL-C

2.44 ± 0.65

0.22

0.675

0.0001

 Hattori LDL-C

2.02 ± 0.63

−0.19

0.899

0.0001

 Anandaraja LDL-C

2.04 ± 0.64

−0.17

0.901

0.0001

 Vujovic LDL-C

2.45 ± 0.64

0.23

0.940

0.0001

 Ahmadi LDL-C

5.55 ± 0.67

3.33

0.160

0.0001

 Puavillai LDL-C

2.34 ± 0.64

0.12

0.933

0.0001

HDL-C 1.03–1.52 mmol/L (n = 1837)

 Direct LDL-C

2.54 ± 0.62

   

 Friedewald LDL-C

2.68 ± 0.74

0.13

0.904

0.0001

 Chen LDL-C

2.70 ± 0.71

0.16

0.933

0.0001

 de Cordova LDL-C

2.56 ± 0.68

0.02

0.905

0.0001

 Hattori LDL-C

2.51 ± 0.70

−0.02

0.903

0.0001

 Anandaraja LDL-C

2.83 ± 0.70

0.29

0.886

0.0001

 Vujovic LDL-C

2.88 ± 0.77

0.33

0.926

0.0001

 Ahmadi LDL-C

4.72 ± 1.72

2.17

0.631

0.0001

 Puavillai LDL-C

2.80 ± 0.76

0.26

0.933

0.0001

HDL-C ≥ 1.55 mmol/L (n = 533)

 Direct LDL-C

2.70 ± 0.73

   

 Friedewald LDL-C

2.93 ± 0.85

0.23

0.974

0.0001

 Chen LDL-C

2.87 ± 0.82

0.16

0.983

0.0001

 de Cordova LDL-C

2.63 ± 0.76

−0.06

0.971

0.0001

 Hattori LDL-C

2.75 ± 0.80

0.05

0.973

0.0001

 Anandaraja LDL-C

3.48 ± 0.79

0.77

0.947

0.0001

 Vujovic LDL-C

3.091 ± 0.89

0.38

0.982

0.0001

 Ahmadi LDL-C

4.32 ± 1.55

1.62

0.806

0.0001

 Puavillai LDL-C

3.03 ± 0.87

0.32

0.980

0.0001

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Lipids in Health and Disease

ISSN: 1476-511X