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Table 4 Mean (±SD) values of calculated LDL-C by eight formulae for various TC ranges and their correlation with directly measured LDL-C

From: Evaluation of eight formulas for LDL-C estimation in Iranian subjects with different metabolic health statuses

Method

Mean ± SD (mmol/L)

Mean Difference (mmol/L)

Correlation (r)

p-value obtained by paired t-test

TC < 5.17 mmol/L (n = 1903)

 Direct LDL-C

2.22 ± 0.42

   

 Friedewald LDL-C

2.30 ± 0.52

0.08

0.885

0.0001

 Chen LDL-C

2.33 ± 0.47

0.11

0.932

0.0001

 de Cordova LDL-C

2.21 ± 0.43

−0.01

0.886

0.354

 Hattori LDL-C

2.15 ± 0.49

−0.06

0.883

0.0001

 Anandaraja LDL-C

2.48 ± 0.55

0.26

0.760

0.0001

 Vujovic LDL-C

2.21 ± 0.52

−0.01

0.923

0.0001

 Ahmadi LDL-C

4.08 ± 1.21

1.86

0.446

0.0001

 Puavillai LDL-C

2.41 ± 0.52

0.19

0.920

0.0001

TC 5.17–6.18 mmol/L (n = 634)

 Direct LDL-C

3.05 ± 0.31

   

 Friedewald LDL-C

3.27 ± 0.47

0.21

0.771

0.0001

 Chen LDL-C

3.30 ± 0.30

0.24

0.792

0.0001

 de Cordova LDL-C

3.13 ± 0.29

0.07

0.400

0.0001

 Hattori LDL-C

3.06 ± 0.44

0.01

0.769

0.327

 Anandaraja LDL-C

3.48 ± 0.51

0.42

0.584

0.0001

 Vujovic LDL-C

3.51 ± 0.37

0.45

0.809

0.0001

 Ahmadi LDL-C

3.17 ± 1.65

0.12

−0.249

0.0001

 Puavillai LDL-C

3.41 ± 0.40

0.36

0.879

0.0001

TC ≥ 6.20 mmol/L (n = 215)

 Direct LDL-C

3.72 ± 0.52

   

 Friedewald LDL-C

4.01 ± 0.91

0.29

0.704

0.0001

 Chen LDL-C

4.13 ± 0.61

0.41

0.602

0.0001

 de Cordova LDL-C

3.99 ± 0.54

0.27

0.161

0.0001

 Hattori LDL-C

3.76 ± 0.87

0.04

0.705

0.337

 Anandaraja LDL-C

4.24 ± 0.94

0.51

0.719

0.0001

 Vujovic LDL-C

4.36 ± 0.75

0.64

0.668

0.0001

 Ahmadi LDL-C

7.77 ± 2.92

4.05

−0.445

0.0001

 Puavillai LDL-C

4.23 ± 0.81

0.51

0.689

0.0001

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Lipids in Health and Disease

ISSN: 1476-511X