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Table 1 Apparent VLDL-TG-secretion abilities in the livers of L1-Tg mice fed a high-fat diet

From: Pathophysiological importance of bile cholesterol reabsorption: hepatic NPC1L1-exacerbated steatosis and decreasing VLDL-TG secretion in mice fed a high-fat diet

Feeding timeEzetimibeApparent VLDL secretion ability [g liver/dL/h]n
0 w40.5 ± 6.1a4
1 w28.8 ± 4.4b7
2 w6.5 ± 0.8c7
2 w+39.1 ± 6.1a4
  1. Values are expressed as the mean ± SEM. Statistical analyses of significant differences among all the groups were performed using Bartlett’s test, followed by a non-parametric Steel–Dwass test for multiple comparisons. Different letters indicate significant differences between groups (P < 0.05); there were no significant differences between the groups indicated by same letters. Time-dependent decrease of apparent VLDL-TG-secretion ability was prevented by ezetimibe administration. VLDL-TG, very low-density lipoprotein-triglyceride; w, weeks. Details are shown in Additional file 1: Figure S5 with a bar chart of this information