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Table 3 Genotype and allele frequency of PNPLA3 I148M in each group

From: Independent and joint correlation of PNPLA3 I148M and TM6SF2 E167K variants with the risk of coronary heart disease in patients with non-alcoholic fatty liver disease

SNP

NAFLD+CHD

(n = 189)

NAFLD

(n = 242)

Control

(n = 266)

NAFLD+CHD vs NAFLD

NAFLD+CHD vs Control

NAFLD vs Control

χ2

P value

χ2

P value

χ2

P value

PNPLA3 I148M

 Genotype

   

9.30

0.01

0.21

0.90

8.36

0.02

  CC

79

73

106

      

  CG

89

121

128

    

  GG

21

48

32

      

 Allele

   

9.13

0.00

0.09

0.77

4.69

0.03

  C

247 (65.34)

267 (55.17)

340 (63.90)

     

  G

131 (34.66)

217 (44.83)

192 (36.09)