Table 2 Comparison of general characteristics and serum levels of biochemical parameters in study participants according to Quintiles of serum levels of uric acid
Variables | 1st Quartile < 213 umol/l (n = 4014) | 2nd Quartile 214–262 umol/l (n = 3515) | 3rd Quartile 263–326 umol/l (n = 3560) | 4th Quartile > 327 umol/l (n = 3529) | P Value | ||||
|---|---|---|---|---|---|---|---|---|---|
n or Mean | % or SD | n or Mean | % or SD | n or Mean | % or SD | n or Mean | % or SD | ||
Age (years) | 48.4 | 12.0 | 50.5 | 12.3 | 52.1 | 12.6 | 52.62 | 13.1 | < 0.001 |
Gender (male), n and % | 1035 | 25.8 | 1275 | 36.3 | 1909 | 53.6 | 2600 | 73.7 | < 0.001 |
History of smoking, n and % | 654 | 16.3 | 778 | 22.1 | 1170 | 32.9 | 1567 | 44.4 | < 0.001 |
Alcohol intake, n and % | 232 | 5.8 | 299 | 8.5 | 582 | 16.4 | 1038 | 29.4 | < 0.001 |
BMI (kg/m2) | 24.9 | 4.2 | 25.3 | 4.2 | 26.1 | 4.3 | 26.91 | 3.9 | < 0.001 |
SBP (mmHg) | 131.4 | 22.5 | 132.8 | 21.9 | 135.7 | 22.2 | 138.2 | 21.5 | < 0.001 |
DBP (mmHg) | 81.2 | 16.6 | 83.2 | 16.6 | 85.3 | 16.9 | 87.9 | 16.8 | < 0.001 |
Hypertension, n and % | 1303 | 32.5 | 1289 | 36.7 | 1509 | 42.4 | 1600 | 45.3 | < 0.001 |
BUN (mmol/L) | 4.6 | 1.5 | 4.8 | 1.5 | 5.1 | 1.5 | 5.4 | 1.7 | < 0.001 |
Creatine (mmol/L) | 61.5 | 24.0 | 68.7 | 23.6 | 75.3 | 23.0 | 86.2 | 26.4 | < 0.001 |
eGFR (ml/min/1.73 m2) | 97.2 | 34.1 | 86.4 | 25.9 | 80.5 | 22.9 | 73.1 | 20.8 | < 0.001 |
FBG (mmol/L) | 5.0 | 1.9 | 5.1 | 1.7 | 5.2 | 1.5 | 5.3 | 1.6 | < 0.001 |
Diabetes | 184 | 4.6 | 185 | 5.3 | 230 | 6.5 | 260 | 7.4 | < 0.001 |
TG (mmol/L) | 1.2 | 0.9 | 1.3 | 1.0 | 1.6 | 1.3 | 2.1 | 1.6 | < 0.001 |
TC (mmol/L) | 4.2 | 1.1 | 4.5 | 1.1 | 4.8 | 1.1 | 5.0 | 1.1 | < 0.001 |