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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Bioinformatics analysis of vascular RNA-seq data revealed hub genes and pathways in a novel Tibetan minipig atherosclerosis model induced by a high fat/cholesterol diet

Fig. 1

Artery vascular pathological assessment in Tibetan minipigs after 24 weeks of continuous feeding with a HFC diet. a Study protocol. 10 Tibetan minipigs were randomly allocated to NC and atherosclerosis groups and fed with a regular diet or a HFC diet throughout the study, and the minipigs were sacrificed at 24 weeks later. b H&E staining of the abdominal aorta and the images of the second line are an enlarged view of the red box in the first line. Triangle represents foam cells, pentagram indicates vascular calcification. c IMT of the abdominal aorta. d Masson staining of the abdominal aorta and the images of the second line are an enlarged view of the red box in the first line. e Aortic lipid analysis by Sudan IV staining. f Percentage of Sudan IV area. Data are expressed as means ± SEM (n = 5). *P < 0.05, **P < 0.01

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