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Table 1 Protective effect methanol extract of M. royleanus leaves on liver and body weight of mice

From: Phytochemical analysis and Evaluation of hepatoprotective effect of Maytenus royleanus leaves extract against anti-tuberculosis drug induced liver injury in mice

Treatments

Liver weight (g)

Initial body weight (g)

Final body weight (g)

Control

6.22 ± 1.36

25.53 ± 0.58

34.7 ± 0.26

RIPE

4.80 ± 0.74*

25.33 ± 0.46

27.1 ± 0.30***

RIPE + MEM (200 mg/kg)

5.71 ± 0.97+

24.83 ± 0.51

31.0 ± 0.39***, +++, ##

RIPE + MEM (400 mg/kg)

5.98 ± 0.13+

25.21 ± 0.39

33.1 ± 0.41+++

RIPE + Vit B6

5.51 ± 1.81+

25.11 ± 0.52

33.4 ± 0.29+++

Vit B6 (180mg/kg) alone

6.28 ± 1.74+

25.30 ± 0.47

35.1 ± 0.30+++

MEM (400 mg/kg) alone

6.06 ± 1.13+

24.71 ± 0.53

34.8 ± 0.37+++

  1. Values are represented as mean ± SEM (n = 6). Data analyzed by one-way analysis of variance followed by multiple comparison test. Asterisks *, **, *** represents significance from control group at p < 0.05, p < 0.001, and p < 0.0001. +, +++ represents significance from RIPE group at p < 0.05 and p < 0.0001 while ### represents significance difference of RIPE + MEM (200 mg/kg) vs RIPE + MEM (400 mg/kg) group at p < 0.0001