Effects of body condition on the insulin resistance, lipid metabolism and oxidative stress of lactating dairy cows

Table 3 Serum biomarkers of liver function and oxidative stress in dairy cows with different body condition score (BCS)

Item²	BCS¹			SEM	P-value
Item²	Low	Medium	High	SEM	P-value
GGT, U/L	26.5	30.1	30.4	1.59	0.19
AST, U/L	67.6	62.9	68.0	2.92	0.39
ALP, U/L	52.3	48.5	51.2	2.70	0.61
Albumin, g/L	30.9^b	31.5^ab	32.3^a	0.35	0.03
Bilirubin, μmol/L	1.89	1.99	1.86	0.06	0.21
SOD, U/mL	62.2	65.0	62.9	2.91	0.78
GSH-Px, U/mL	163	159	169	8.2	0.64
PON, IU/L	841	812	875	48.3	0.59
Ceruloplasmin, U/L	18.1^b	27.1^a	23.8^ab	2.11	0.02
Myeloperoxidase, U/L	9.40	9.62	8.94	0.41	0.47
ROS, IU/mL	134^ab	140^a	127^b	3.1	< 0.01
MDA, nmol/mL	7.40	6.60	7.13	0.42	0.41

^a-bMeans within same row with different superscripts differ (P < 0.05)
¹Low: BCS ≤ 2.75 (n = 12); Medium: 3.0 ≤ BCS ≤ 3.5 (n = 15); BCS ≥ 3.75 (n = 15)
²GGT gamma-glutamyltranspeptidae; AST aspartate aminotransferase; ALP alkaline phosphatase; SOD superoxide dismutase; GSH-Px glutathione peroxidase; PON paraoxonase; ROS reactive oxygen species; MDA malondiadehyde

ISSN: 1476-511X