A genetic variant in the promoter of lncRNA MALAT1 is related to susceptibility of ischemic stroke

Table 6 Association between the MALAT1 SNPs and blood lipid levels in IS

SNPs	TC, mmol/L	TG, mmol/L	HDL-C, mmol/L	LDL-C, mmol/L	Apo-A1, g/L	Apo-B, g/L	NEFA, mmol/L
rs600231
AA	4.65 ± 1.20	1.79 ± 1.34	1.13 ± .33	2.94 ± 1.03	1.23 ± 0.26	1.00 ± 0.32	0.53 ± 0.28
AG/GG	4.64 ± 1.08	1.83 ± 1.27	1.12 ± .31	2.88 ± 0.90	1.23 ± 0.25	1.00 ± 0.30	0.55 ± 0.28
t	0.090	−0.245	0.384	0.462	−0.138	0.007	−0.620
p	0.928	0.806	0.701	0.645	0.890	0.995	0.535
rs1194338
CC	4.68 ± 1.11	1.79 ± 1.38	1.14 ± 0.32	2.94 ± 0.97	1.23 ± 0.23	0.99 ± 0.30	0.52 ± 0.27
AC/AA	4.62 ± 1.19	1.82 ± 1.27	1.12 ± 0.32	2.90 ± 0.99	1.23 ± 0.28	1.01 ± 0.31	0.54 ± 0.29
t	0.478	−0.170	0.519	0.434	−0.032	−0.382	0.498
p	0.633	0.865	0.604	0.664	0.974	0.703	0.619
rs4102217
GG	4.52 ± 1.21	1.72 ± 1.20	1.12 ± 0.30	2.80 ± 0.99	1.21 ± 0.26	0.98 ± 0.30	0.55 ± 0.29
CG/CC	4.68 ± 1.14	1.83 ± 1.35	1.13 ± 0.33	2.96 ± .98	1.24 ± 0.26	1.01 ± 0.31	0.53 ± 0.28
t	−1.079	−0.677	−0.374	−1.274	−0.642	− 0.861	0.562
p	0.281	0.499	0.708	0.204	0.522	0.390	0.574
rs591291
CC	4.64 ± 1.22	1.82 ± 1.40	1.13 ± 0.33	2.93 ± 1.05	1.23 ± 0.27	1.00 ± 0.32	0.53 ± 0.28
CT/TT	4.63 ± 1.07	1.78 ± 1.19	1.12 ± 0.31	2.89 ± 0.88	1.24 ± 0.25	1.00 ± 0.29	0.54 ± 0.28
t	0.072	0.262	0.124	0.460	−0.447	0.083	− 0.550
p	0.943	0.794	0.902	0.646	0.655	0.934	0.583

TC Total cholesterol, TG Triglyceride, HDL-C High density lipoprotein-cholesterol, LDL-C Low density lipoprotein-cholesterol, Apo-A1 Apolipoprotein A1, Apo-B, Apolipoprotein B, NEFA Non-esterified fatty acid

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