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Table 3 Predictors of long-term mortality in univariable and multivariable Cox regression analyses

From: Neutrophil to high-density lipoprotein ratio has a superior prognostic value in elderly patients with acute myocardial infarction: a comparison study

Variables

Univariable

Multivariable

Hazard ratio (95% CI)

P

Hazard ratio (95% CI)

P

Age, year

1.09 (1.04 to 1.13)

< 0.001

–

0.268

Gender (male)

1.73 (1.10 to 2.71)

0.017

–

0.066

Gensini score

1.01 (1.00 to 1.01)

0.009

1.00 (1.00 to 1.01)

0.034

Smoking status

1.53 (0.94 to 2.50)

0.087

–

0.814

Hypertension

1.09 0.69 to 1.73)

0.703

–

0.877

Prior CAD

1.47 (0.82 to 2.62)

0.196

–

0.245

Diabetes

1.85 (1.17 to 2.94)

0.009

–

0.225

Killip class

2.14 (1.73 to 2.64)

< 0.001

1.85 (1.48 to 2.31)

< 0.001

LVEF

0.97 (0.95 to 0.98)

< 0.001

–

0.274

CTnI

1.97 (1.26 to 3.09)

0.003

–

0.333

WBC

1.16 (1.11 to 1.23)

< 0.001

1.09 (1.03 to 1.16)

0.005

Neutrophil

1.17 (1.11 to 1.22)

< 0.001

–

0.866

Lymphocyte

0.89 (0.62 to 1.26)

0.499

  

Monocyte

2.84 (1.50 to 5.37)

0.001

–

0.496

Platelet

1.00 (1.00 to 1.01)

0.102

  

Hemoglobin

0.98 (0.97 to 0.99)

< 0.001

0.98 (0.97 to 0.99)

0.001

Total cholesterol

1.12 (0.93 to 1.35)

0.246

  

Total triglyceride

0.95 (0.76 to 1.18)

0.628

  

HDL-C

0.64 (0.35 to 1.16)

0.139

  

LDL-C

1.18 (0.95 to 1.48)

0.130

  

Creatinine

1.01 (1.01 to 1.02)

< 0.001

–

0.207

NHR ≥ 5.74

3.21 (1.87 to 5.50)

< 0.001

1.96 (1.02 to 3.75)

0.044

MHR ≥ 0.67

2.22 (1.42 to 3.49)

0.001

–

0.237

LDL-C/HDL-C ≥ 3.57

1.25 (1.59 to 4.11)

0.010

–

0.092

  1. CI confidence interval, CAD coronary artery disease, LVEF left ventricular ejection fraction, CTnI cardiac troponin I, WBC white blood cell, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, NHR neutrophil to high-density lipoprotein cholesterol ratio, MHR monocyte to high-density lipoprotein, LDL-C/HDL-C low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio
  2. Note: Bolded differences show statistical difference at the p < 0.05 for multivariate analysis