Table 1 Baseline patient characteristics according to LDL-C/HDL-C tertile
Characteristic | Total (n = 1616) | LDL-C/HDL-C Ratio Tertile | P-value | ||
|---|---|---|---|---|---|
T1 (< 2.04) (n = 539) | T2 (2.04–2.74) (n = 538) | T3 (≥2.74) (n = 539) | |||
Age (years) | 47.5 ± 15.2 | 46.0 ± 15.1 | 47.4 ± 15.3 | 49.2 ± 15.1 | 0.003 |
Male gender, n (%) | 966 (59.8) | 239 (44.3) | 215 (40.0) | 196 (36.4) | 0.028 |
BMI (kg/m2) | 21.6 ± 3.1 | 20.8 ± 2.9 | 21.6 ± 3.2 | 22.4 ± 3.1 | < 0.001 |
Systolic pressure (mmHg) | 136.5 ± 19.8 | 136.4 ± 19.8 | 136.0 ± 19.8 | 137.2 ± 19.7 | 0.575 |
Diastolic pressure (mmHg) | 84.7 ± 14.4 | 84.8 ± 15.0 | 85.3 ± 13.7 | 84.2 ± 14.5 | 0.468 |
Diabetes, n (%) | 415 (25.7) | 122 (22.6) | 125 (23.2) | 168 (31.2) | 0.002 |
CVD n (%) | 596 (36.9) | 202 (37.5) | 192 (35.7) | 202 (37.5) | 0.781 |
Hypertension, n (%) | 1439 (89.0) | 484 (89.8) | 470 (87.4) | 485 (90.0) | 0.307 |
Total cholesterol (mg/dL) | 196.5 ± 51.4 | 174.5 ± 43.7 | 194.4 ± 43.3 | 220.4 ± 55.8 | < 0.001 |
Triglycerides (mg/dL) | 124.8 (89.4–177.0) | 95.6 (70.3–137.2) | 127.4 (94.7–171.7) | 154.9 (114.2–210.2) | < 0.001 |
HDL-C (mg/dL) | 47.6 ± 14.9 | 56.5 ± 16.7 | 46.9 ± 11.8 | 39.5 ± 10.3 | < 0.001 |
LDL-C (mg/dL) | 113.3 ± 38.8 | 88.6 ± 26.7 | 111.3 ± 27.9 | 140.1 ± 41.0 | < 0.001 |
LDL-C/HDL-C | 2.5 ± 1.0 | 1.6 ± 0.3 | 2.4 ± 0.2 | 3.6 ± 0.9 | < 0.001 |
Non-HDL-C (mg/dL) | 148.8 ± 48.1 | 118.1 ± 34.4 | 147.5 ± 35.5 | 181.0 ± 50.2 | < 0.001 |
Hemoglobin (g/L) | 105.0 ± 21.2 | 103.1 ± 21.7 | 106.8 ± 21.2 | 105.1 ± 20.5 | 0.014 |
Serum albumin (g/L) | 37.3 ± 5.2 | 37.2 ± 5.0 | 37.6 ± 5.0 | 37.0 ± 5.4 | 0.128 |
Creatinine (mg/dL) | 8.7 ± 3.2 | 8.7 ± 3.3 | 8.6 ± 3.1 | 8.8 ± 3.4 | 0.373 |
Uric acid (μmol/L) | 417.2 ± 91.9 | 408.4 ± 94.2 | 415.1 ± 85.8 | 428.0 ± 94.4 | 0.002 |
Hs-CRP (mg/L) | 1.8 (0.6–5.7) | 1.2 (0.4–3.6) | 1.5 (0.7–5.7) | 2.9 (1.0–8.1) | < 0.001 |
eGFR (mL/min/1.73 m2) | 6.9 ± 3.1 | 6.8 ± 3.0 | 7.0 ± 3.4 | 6.7 ± 3.0 | 0.431 |
Kt/V | 2.5 ± 0.7 | 2.5 ± 0.7 | 2.5 ± 0.6 | 2.4 ± 0.7 | 0.750 |
Statins n (%) | 236 (14.6) | 91 (16.9) | 71 (13.2) | 74 (13.7) | 0.180 |