Skip to main content

Table 2 The association of LDL-C/HDL-C ratio with CVD and all-cause mortalities in the study cohort

From: The predictive study of the relation between elevated low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and mortality in peritoneal dialysis

 

LDL-C/HDL-C Tertile

HR per 0.5 increased

T1

T2

T3

CVD mortality

 Event rate, %

13.0

13.8

18.9

15.2

 Events/total

70/539

74/538

102/539

246/1616

HR (95% CI), P-value

 Unadjusted

1 [reference]

1.113 (0.802–1.543)

0.522

1.689 (1.244–2.291)

0.001

1.112 (1.056–1.171)

< 0.001

 Model 1

1 [reference]

1.079 (0.777–1.496)

0.651

1.471 (1.084–1.998)

0.013

1.087 (1.027–1.150)

0.004

 Model 2

1 [reference]

1.121 (0.805–1.561)

0.498

1.476 (1.079–2.018)

0.015

1.079 (1.018–1.144)

0.010

 Model 3

1 [reference]

1.338 (0.901–1.987)

0.149

1.732 (1.191–2.518)

0.004

1.110 (1.037–1.188)

0.003

 Model 4

1 [reference]

1.423 (0.954–2.122)

0.084

1.880 (1.280–2.760)

0.001

1.123 (1.049–1.202)

0.001

All-cause mortality

 Event rate, %

28.6

27.0

35.8

30.4

 Events/total

154/539

145/538

193/539

492/1616

HR (95% CI), P-value

 Unadjusted

1 [reference]

0.994 (0.792–1.247)

0.958

1.462 (1.182–1.808)

0.001

1.099 (1.058–1.142)

< 0.001

 Model 1

1 [reference]

0.952 (0.759–1.195)

0.673

1.255 (1.014–1.552)

0.037

1.070 (1.027–1.115)

0.001

 Model 2

1 [reference]

0.984 (0.782–1.237)

0.887

1.248 (1.004–1.553)

0.046

1.065 (1.020–1.110)

0.004

 Model 3

1 [reference]

1.077 (0.817–1.420)

0.597

1.318 (1.010–1.721)

0.042

1.073 (1.018–1.131)

0.009

 Model 4

1 [reference]

1.094 (0.828–1.446)

0.529

1.345 (1.026–1.765)

0.032

1.077 (1.021–1.136)

0.006

  1. Model 1: Adjusted for age and gender
  2. Model 2: Adjusted for model 1 covariates and diabetes, history of cardiovascular events, BMI, and systolic blood pressure
  3. Model 3: Adjusted for model 2 covariates and hemoglobin, serum albumin, uric acid, serum Cr, hs-CRP, Kt/V, and eGFR
  4. Model 4: Adjusted for model 3 covariates and statin use
  5. P < 0.05 is considered to be statistically significant