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Table 1 Clinical characteristics at baseline parameters and of all subjects

From: Fenofibrate decreased microalbuminuria in the type 2 diabetes patients with hypertriglyceridemia

Group

Control group (n = 28)

Fenofibrate group (n = 28)

P

Sex (male/%)

17/60.7

20/71.4

0.604

Age (year)

56.03±12.32

54.64±10.09

0.593

Duration of diabetes (years)

5.21±2.02

5.83±1.39

0.716

Hypertension (number/%)

10/35.7

11/39.3

0.500

AECI/ARB (number/%)

7/25.0

8/28.6

0.768

CCB (number/%)

5/17.9

5/17.9

0.636

Metformin (number/%)

15, 53.6

13, 46.4

0.601

α-Glucosidase inhibitors (number/%)

20, 71.42

22, 78.6

0.546

Sulfonylureas (number/%)

12, 42.9

11, 39.3

0.791

Glinides (number/%)

10, 35.7

11, 39.3

0.787

Insulin (number/%)

6, 21.4

8, 28.6

0.786

Insulin/Oral medications (%)

22.2

28.6

0.372

Simvastatin (number/%)

12/42.9

10/35.7

0.392

Atorvastatin (number/%)

9/28.0

10/35.7

0.591

Rosuvastatin (number/%)

3/10.7

2/7.1

0.500

pravastatin(number/%)

4/14.3

6/21.4

0.364

SBP (mmHg)

137.75±13.77

137.71±9.59

0.996

DBP (mmHg)

75.00±5.60

76.29±7.87

0.782

BMI, kg/m2

27.28±3.99

28.32±4.36

0.429

FPG, mmol/L

7.92±2.16

8.27±1.31

0.606

HbA1c, %

7.62±0.87

7.48±0.86

0.480

TG, mmol/L

2.97(2.13,3,31)

3.04(2.21, 3.29)

0.606

TC, mmol/L

4.59±1.14

4.79±1.01

0.474

LDL-C, mmol/L

2.47±0.90

2.55±0.94

0.670

HDL-C, mmol/L

1.02±0.20

1.09±0.24

0.275

Scr, μmol/L

69.56±15.43

65.46±20.98

0.349

UA, μmol/L

388.44±126.99

372.46 ± 72.78

0.803

UACR, mg/g

105.00(64.00, 165.00)

129.00 (53.00, 226.25)

0.095

eGFR ml/min/1.73m2

94.01 (80.95, 120.95)

105.36 (99.68, 116.92)

0.066

FINS, μIU/mL

12.9 (6.75, 15.78)

12.05 (8.35, 14.95)

0.101

HOMA-IR

4.50 (3.13, 5.95)

4.27 (3.05, 5.35)

0.105

HOMA-β

42.04 (25.33,75.23)

49.51 [35.85, 70.05]

0.127

  1. Data are means ± SD or medians (interquartile range) or n (%)
  2. AECI/ARB Angiotensin Converting Enzyme Inhibitors/Angiotensin receptor antagonist, CCB Ca-Antagonists, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, FBG fasting blood glucose, TG triglycerides, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, Scr serum creatinine, UA uric acid, UACR urinary albumin creatinine ratio, eGFR estimated glomerular filtration rate, FINS fasting serum insulin, HOMA-IR homeostasis model assessment for insulin resistance, HOMA-β homeostasis model assessment for β-cell function