Table 2 The changes of Clinical characteristics after 90 and 180 days follow up
From: Fenofibrate decreased microalbuminuria in the type 2 diabetes patients with hypertriglyceridemia
Group | Control (n = 28) | Fenofibrate treatment (n = 28) |
|---|---|---|
SBP (mmHg) | ||
90 days | -2.00(-7.00,3.00) | -1.00(-3.00, -1.00) |
180 days | -2.50(-8.00, 5.00) | -1.00(-7.00, 4.00) |
DBP ( mmHg) | ||
90 days | -0.80(-3.00, 4.00) | -1.00(-3.00, -1.00) |
180 days | -1.00(-2.00, 5.00) | -1.20(-2.00, 0.25) |
BMI, kg/m2 | ||
90 days | -0.26(-1.56,0.12) | -0.20(-1.16,0.15) |
180 days | -0.22(-1.32,0.17) | -0.21(-1.01,0.22) |
FPG, mmol/L | ||
90 days | -0.43(-1.70,0.50) | -0.37(-1.77, 0.32) |
180 days | -0.24(-2.44, 0.39) | -0.68(-2.81,0.19) |
HbA1c, % | ||
90 days | -0.60(-1.30,0.10) | -0.40(-1.35, -0.10) |
180 days | -0.90(-1.40, -0.25) | -0.70(-1.38, -0.10) |
TG, mmol/L | ||
90 days | -0.64(-0.96,0.42) | -1.27(-1.77, -0.24) * |
180 days | -0.22(-1.21,0.19) | -1.91(-1.12, -0.53) # |
TC, mmol/L | ||
90 days | -0.19(-1.26,0.11) | -0.19(-0.77, -0.19) |
180 days | 0.22(-0.29, 0.53) | -0.21 (-0.87,0.31) |
LDL-C, mmol/L | ||
90 days | -0.10(-0.80,0.10) | -0.15(-0.50, 0.72) |
180 days | 0.25(-0.18, 0.40) | -0.20(-0.40,0.40) |
HDL-C, mmol/L | ||
90 days | 0.00(0.00,0.01) | 0.20(0.10,0.20) * |
180 days | 0.00(0.00,0.01) | 0.16(0.00,0.22) # |
Scr, μmol/L | ||
90 days | 1.70(-2.40,5.20) | 7.60(3.80, 12.40) * |
180 days | 4.35(-0.95, 9.80) | 4.25 (-1.75, 15.60) |
UA, μmol/L | ||
90 days | 0.00(-60.00,45.00) | -92.5(-145, -21) * |
180 days | -16.00(-43.75, -16.00) | -66(-111.00, -34.00) # |
UACR, mg/g | ||
90 days | -20.87(-61.16,15.72) | -41.39(-103.81, -1.44) |
180 days | -8.15(-59.69, 41.94) | -44.05(-179.47, -12.16) # |
eGFR ml/min/1.73m2 | ||
90 days | -2.27(-7.33,4.63) | -9.25(-22.10, -8.28) * |
180 days | -5.63(-12.10,1.12) | -7.26(-21.34, -1.37) |
FINS, μIU/mL | ||
90 days | -0.60(-3.45,2.12) | -0.90(-4.50,2.10) |
180 days | -0.25(-5.15, 2.35) | -1.40(-6.90, 1.81) |
HOMA-IR | ||
90 days | -0.35(-1.98,0.64) | -0.25(-2.77, 0.45) |
180 days | -1.09(-2.68, -1.09) | -0.94(-3.15, 0.58) |
HOMA-β | ||
90 days | 6.19(-38.88, 20.64) | 3.62(-6.21,25.04) |
180 days | 6.98(-39.58, 34.25) | 4.75(-21.91, 30.38) |