The C18:3n6/C22:4n6 ratio is a good lipid marker of chronic kidney disease (CKD) progression

Szczuko, Małgorzata; Kaczkan, Małgorzata; Małgorzewicz, Sylwia; Rutkowski, Przemysław; Dębska-Ślizień, Alicja; Stachowska, Ewa

doi:10.1186/s12944-020-01258-y

Lipids in Health and Disease

Table 6 Correlation matrix of the biochemical parameters of women with CKD vs. FFA (selected); p < 0.05

From: The C18:3n6/C22:4n6 ratio is a good lipid marker of chronic kidney disease (CKD) progression

Parameter	C10:0 Capric acid	C14:0 Myristic acid	C16:0 Palmitic acid	C16:1 Palmitoleic acid	C18:0 Stearic acid	C18:1n9 ct Oleic acid	C18:2n6c acid	C18:3n6 γ-linoleic acid	C20:5n3 EPA	C22:2 cis-docodienoic acid	C22:4n6 (docosatetraenoate)
Age	0.135	0.090	0,137	0,098	-0,049	−0.193	−0.188	0.226	0.324	−0.080	0.053
Ca [mg/dl]	−0.093	0.310	0,058	0,322	−0,228	0.128	−0.556	0.242	0.760	0.430	−0.433
I PHOS [mg/dl]	−0.171	−0.093	−0,270	−0,210	0,321	0.340	−0.140	−0.105	−0.066	−0.072	−0.423
iPTH [pg/ml]	−0.201	0.027	−0,053	−0,116	0,172	0.236	−0.190	−0.070	−0.072	0.660	−0.056
CREA [mg/dl]	0.103	0.163	0,027	0,146	0,026	−0.123	0.207	− 0.230	− 0.167	− 0.212	0.451
HGB [g/dl]	0.482	0.118	0,268	0,328	− 0,212	− 0.269	− 0.178	0.250	0.298	0.022	0.341
%TSAT [%]	− 0.068	0.150	0,517	0,359	−0,477	0.595	0.177	0.350	0.316	−0.013	0.437
Transferrin	0.428	− 0.092	− 0,166	0,068	− 0,059	0.092	0.090	0.030	0.104	− 0.025	− 0.097
FER [ug/l]	− 0.280	0.059	− 0,095	0,059	− 0,327	0.563	− 0.232	0.328	0.490	0.827	− 0.042
ALB [g/l]	− 0.827	− 0.067	− 0,033	0,143	0,157	0.301	0.014	0.526	0.212	0.069	−0.594
Na [mEq/L]	−0.064	− 0.355	− 0,415	0,219	− 0,007	−0.397	0.354	−0.035	− 0.303	−0.583	0.405
K [mEq/L]	0.212	−0.318	−0,567	− 0,603	0,414	− 0.708	0.835	− 0.746	−0.777	− 0.743	0.541
Height [cm]	0.468	−0.804	−0,424	− 0,237	0,109	− 0.760	0.821	− 0.551	−0.711	− 0.287	0.926
Weight after [kg]	−0.129	0.388	0,026	0,258	0,111	0.448	−0.372	0.366	0.183	0.030	−0.237
Treatment duration [months]	−0.115	−0.152	− 0,030	0,006	− 0,127	0.021	0.036	−0.291	− 0.106	0.017	0.413
BMI	−0.048	0.355	−0,015	0,335	−0,146	0.494	−0.415	0.394	0.159	0.107	−0.179
Body Surface [m2]	−0.172	0.408	0,062	0,181	−0,225	0.369	−0.310	0.358	0.211	−0.030	−0.290
Kt/V	0.193	−0.347	−0,054	− 0,248	−0,039	− 0.454	0.254	− 0.330	−0.176	− 0.379	0.369
CRP	0.536	−0.107	−0,084	− 0,034	0,207	0.064	0.172	−0.345	−0.118	− 0.052	0.091
nPCR [g/kg/day]	−0.024	0.062	0,289	−0,030	−0,017	− 0.017	−0.073	− 0.022	−0.230	− 0.293	0.176
Ca x P [mg2/dl2]	−0.025	0.242	0,189	0,152	−0,168	−0.168	0.084	0.166	−0.011	−0.040	0.352

* Average treatment duration 62.42 months; bold text - statistically significant correlation

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